Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17250046 | 0.84 | THRB (0.48) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL23746701 | 0.83 | ALDH1A1 (0.50) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL6060478 | 0.83 | TSHR (0.45) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL17676406 | 0.81 | THRB (0.46) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL4120854 | 0.81 | TSHR (0.44) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL22217175 | 0.79 | TSHR (0.42) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL5576280 | 0.79 | TSHR (0.45) | TSHRALDH1A1THRBMAPK1TDP1 | |
| SCHEMBL8517689 | 0.79 | THRB (0.48) | TSHRALDH1A1THRBMGAMGAA | |
| SCHEMBL1548496 | 0.79 | — | — | |
| SCHEMBL685408 | 0.78 | THRB (0.52) | TSHRALDH1A1THRBKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3910003-A1 | POLYAMIDE-IMIDE BLOCK COPOLYMER, METHOD FOR PREPARING SAME, AND POLYAMIDE-IMIDE FILM COMPRISING SAME | LG Chem, Ltd. (KR) | 2021-11-17 | — | — | EP | disclosed |
| US-8357771-B2 | Production of ophthalmic devices based on photo-induced step growth polymerization | NOVARTIS AG (CH) | 2013-01-22 | — | — | US | disclosed |
| US-20110269869-A1 | PRODUCTION OF OPHTHALMIC DEVICES BASED ON PHOTO-INDUCED STEP GROWTH POLYMERIZATION | ALCON INC. (CH) | 2011-11-03 | — | — | US | disclosed |
| US-7977430-B2 | Prepared by reacting an amine- or isocyanate-capped polyurea with a multifunctional compound having at least one one ethylenically unsaturated group and a function group coreactive with the capping amine or isocyanate groups of the polyurea; soft contact lenses; durability | NOVARTIS AG (CH) | 2011-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269869-A1 | PRODUCTION OF OPHTHALMIC DEVICES BASED ON PHOTO-INDUCED STEP GROWTH POLYMERIZATION | CRYAA, CRYZ, CRYAB | TSHR 3392/4885ALDH1A1 2409/4885THRB 4033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.