SCHEMBL14749076

SCHEMBL14749076

CCC1(OC(=O)c2cccc3c(OC(=O)C(C)(C)CC)cccc23)CCCC1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.34
ESR2 Q92731 5/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
ELANE P08246 3/20 0.33
GAA P10253 2/20 0.33
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
POLB P06746 1/20 0.31
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12014441 0.81 ADRB2 (0.31)
SCHEMBL10064125 0.79 ESR1 (0.39) ESR1ESR2KMT2AMEN1ELANE
SCHEMBL13408039 0.77 ELANE (0.42) ESR1ESR2KMT2AMEN1ELANE
SCHEMBL26791203 0.75 CA12 (0.36) KMT2AMEN1ELANEGAAPOLB
SCHEMBL18135082 0.73 ESR1 (0.44) ESR1ESR2KMT2AMEN1ELANE
SCHEMBL12015393 0.73 CNR2 (0.39) KMT2AMEN1ALDH1A1SMN1; SMN2POLB
SCHEMBL6400218 0.73 TSHR (0.46) KMT2AMEN1ALDH1A1SMN1; SMN2POLB
SCHEMBL15447048 0.72 LMNA (0.45) ELANEGAAALDH1A1SMN1; SMN2CNR1
SCHEMBL17812507 0.72 TSHR (0.35) KMT2AMEN1ELANEGAAALDH1A1
SCHEMBL12014453 0.72 ACE2 (0.37) KMT2AMEN1CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8778592-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-07-15 US disclosed
US-8652756-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-02-18 US disclosed
US-8574816-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-11-05 US disclosed
US-20130056653-A1 POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-03-07 US disclosed
US-20130056654-A1 POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-03-07 US disclosed