Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743630 | 0.88 | RAB9A (0.53) | RAB9ANPC1ATMPOLBMAP4K4 | |
| SCHEMBL25385568 | 0.85 | NPC1 (0.53) | RAB9ANPC1ATMPOLBMAP4K4 | |
| SCHEMBL12553696 | 0.85 | NPC1 (0.53) | RAB9ANPC1ATMPOLBMAP4K4 | |
| SCHEMBL2727656 | 0.82 | HPGD (0.54) | RAB9ANPC1ATMPOLBKDM4E | |
| SCHEMBL11833701 | 0.81 | HPGD (0.55) | RAB9ANPC1POLBCNR1CNR2 | |
| SCHEMBL1933162 | 0.81 | RAB9A (0.53) | RAB9ANPC1ATMPOLBCNR1 | |
| SCHEMBL11838628 | 0.80 | RAB9A (0.48) | RAB9ANPC1ATML3MBTL1MAPT | |
| SCHEMBL1933702 | 0.79 | NPC1 (0.48) | RAB9ANPC1ATMKDM4EDGAT2 | |
| SCHEMBL4240834 | 0.79 | OGG1 (0.53) | RAB9ANPC1ATMPOLBKDM4E | |
| SCHEMBL2759010 | 0.77 | NPC1 (0.61) | RAB9ANPC1ATMPOLBMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701841-B2 | Cell permeable, fluorescent dye | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2017-07-11 | — | — | US | disclosed |
| US-9701841-B2 | Cell permeable, fluorescent dye | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2017-07-11 | — | — | US | disclosed |
| US-9701841-B2 | Cell permeable, fluorescent dye | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2017-07-11 | — | — | US | disclosed |
| EP-2748173-B1 | CELL PERMEABLE, FLUORESCENT DYE | ECOLE POLYTECH (CH) | 2016-11-23 | — | — | EP | disclosed |
| EP-2748173-B1 | CELL PERMEABLE, FLUORESCENT DYE | ECOLE POLYTECH (CH) | 2016-11-23 | — | — | EP | disclosed |
| US-20160230011-A1 | CELL PERMEABLE, FLUORESCENT DYE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2016-08-11 | — | — | US | disclosed |
| US-20160230011-A1 | CELL PERMEABLE, FLUORESCENT DYE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2016-08-11 | — | — | US | disclosed |
| US-20160230011-A1 | CELL PERMEABLE, FLUORESCENT DYE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2016-08-11 | — | — | US | disclosed |
| US-9346957-B2 | Cell permeable, fluorescent dye | ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) (CH) | 2016-05-24 | — | — | US | disclosed |
| US-9346957-B2 | Cell permeable, fluorescent dye | ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) (CH) | 2016-05-24 | — | — | US | disclosed |
| US-9346957-B2 | Cell permeable, fluorescent dye | ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) (CH) | 2016-05-24 | — | — | US | disclosed |
| US-20140349282-A1 | Cell Permeable, Fluorescent Dye | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2014-11-27 | — | — | US | disclosed |
| US-20140349282-A1 | Cell Permeable, Fluorescent Dye | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2014-11-27 | — | — | US | disclosed |
| US-20140349282-A1 | Cell Permeable, Fluorescent Dye | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2014-11-27 | — | — | US | disclosed |
| WO-2013029650-A1 | CELL PERMEABLE, FLUORESCENT DYE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2013-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160230011-A1 | CELL PERMEABLE, FLUORESCENT DYE | EPCAM, IK, TSPO | RAB9A 260/4885NPC1 941/4885ATM 2561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.