Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 19/20 | 0.83 |
| ▸ | IMPDH1 | P20839 | 15/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | HPGD | P15428 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.78 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.74 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.74 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.74 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.74 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.74 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.74 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.74 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18538602 | 0.93 | IMPDH2 (0.85) | IMPDH2IMPDH1ALDH1A1LMNAHPGD | |
| SCHEMBL29463203 | 0.91 | IMPDH2 (1.00) | IMPDH2IMPDH1ALDH1A1LMNAHPGD | |
| SCHEMBL1375645 | 0.91 | IMPDH2 (1.00) | IMPDH2IMPDH1ALDH1A1LMNAHPGD | |
| SCHEMBL1152477 | 0.91 | IMPDH2 (1.00) | IMPDH2IMPDH1ALDH1A1LMNAHPGD | |
| SCHEMBL24420499 | 0.90 | IMPDH2 (0.86) | IMPDH2IMPDH1ALDH1A1LMNAHPGD | |
| SCHEMBL18542936 | 0.89 | IMPDH2 (0.85) | IMPDH2IMPDH1ALDH1A1LMNAHPGD | |
| SCHEMBL13058820 | 0.89 | IMPDH2 (0.86) | IMPDH2IMPDH1ALDH1A1LMNAHPGD | |
| SCHEMBL13985606 | 0.89 | IMPDH2 (0.77) | IMPDH2IMPDH1ALDH1A1LMNAHPGD | |
| SCHEMBL9449404 | 0.88 | IMPDH2 (0.76) | IMPDH2IMPDH1ALDH1A1LMNAHPGD | |
| Mycophenolic Acid SCHEMBL1230249 | 0.88 | IMPDH2 (1.00) | IMPDH2IMPDH1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029479-A1 | MYCOPHENOLIC ACID DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | 中国科学院上海药物研究所 (CN) | 2013-03-07 | — | — | WO | disclosed |