SCHEMBL14749252

SCHEMBL14749252

CC(=O)c1cc(C)oc1C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.38
KDM4E B2RXH2 4/20 0.38
NOTUM Q6P988 1/20 0.37
HTT P42858 2/20 0.37
HPGD P15428 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
HTR1A P08908 1/20 0.36
HTR1D P28221 1/20 0.36
HTR1B P28222 1/20 0.36
SCD O00767 1/20 0.35
AURKA O14965 1/20 0.35
RPS6KB1 P23443 1/20 0.35
AURKB Q96GD4 1/20 0.35
ALDH1A1 P00352 6/20 0.35
GAA P10253 2/20 0.35
PKM P14618 1/20 0.35
PAX8 Q06710 1/20 0.35
RAB9A P51151 2/20 0.34
RECQL P46063 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL885485 0.85 NOTUM (0.49) MAPTKDM4ENOTUMHTTHPGD
SCHEMBL420546 0.83 L3MBTL1 (0.43) MAPTKDM4ENOTUMHTTHPGD
SCHEMBL3061999 0.83 MAPT (0.41) MAPTKDM4ENOTUMHTTHPGD
SCHEMBL2305192 0.80 MAPT (0.42) MAPTKDM4EHPGDSMN1; SMN2SCD
SCHEMBL13485763 0.80 KDM4E (0.42) MAPTKDM4EHPGDSMN1; SMN2SCD
SCHEMBL2308270 0.80 ALDH1A1 (0.39) MAPTKDM4ENOTUMHTTHPGD
SCHEMBL13753597 0.78 POLB (0.44) MAPTKDM4EHPGDSMN1; SMN2SCD
SCHEMBL2280370 0.78 GAA (0.54) MAPTKDM4ESMN1; SMN2ALDH1A1GAA
SCHEMBL13753336 0.76 MAPT (0.48) MAPTKDM4EHPGDSMN1; SMN2SCD
SCHEMBL13753406 0.76 NPSR1 (0.43) MAPTKDM4EHTTSMN1; SMN2AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8785662-B2 Anilide-based compounds for preserving wood and method of use thereof SDS BIOTECH K.K. (JP) 2014-07-22 US disclosed
US-20130059014-A1 PRESERVATIVE FOR PRESERVING WOOD AND METHOD FOR TREATING WOOD SDS BIOTECH K. K. (JP) 2013-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130059014-A1 PRESERVATIVE FOR PRESERVING WOOD AND METHOD FOR TREATING WOOD ALKBH5, DCXR, AKR7A2 MAPT 1158/4885KDM4E 44/4885NOTUM 143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.