SCHEMBL1475428

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1476193	0.87	ALDH1A1 (0.46)	L3MBTL1LMNAABL1RIN1ALDH1A1
	SCHEMBL1475323	0.86	SIGMAR1 (0.45)	ACKR3L3MBTL1ABL1RIN1ALDH1A1
	SCHEMBL1476187	0.85	SIGMAR1 (0.45)	ACKR3ALDH1A1KMT2ACYP2D6KDM4E
	SCHEMBL12827515	0.85	L3MBTL1 (0.38)	ACKR3L3MBTL1PARP1ABL1RIN1
	SCHEMBL1475069	0.85	SIGMAR1 (0.43)	L3MBTL1ALDH1A1POLBKMT2AKDM4E
	SCHEMBL1476152	0.85	SIGMAR1 (0.43)	ACKR3L3MBTL1PARP1LMNAABL1
	SCHEMBL1474298	0.85	SIGMAR1 (0.46)	ACKR3LMNAALDH1A1KMT2AMAPT
	SCHEMBL1476039	0.84	F10 (0.38)	ACKR3L3MBTL1PARP1LMNAABL1
	SCHEMBL1474233	0.84	MAPT (0.50)	LMNAALDH1A1POLBKMT2AMAPT
	SCHEMBL1476249	0.83	CD274 (0.40)	L3MBTL1LMNAABL1RIN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.