SCHEMBL1475490

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1474694	0.92	ALDH1A1 (0.46)	SIGMAR1ALDH1A1TDP1MAPTHTR2A
	SCHEMBL1475069	0.88	SIGMAR1 (0.43)	SIGMAR1ALDH1A1HTR2AKMT2ACACNA1G
	SCHEMBL1475174	0.86	HTR2A (0.42)	SIGMAR1HTR2ACACNA1GF10
	SCHEMBL1475172	0.84	ACKR3 (0.37)	SIGMAR1ALDH1A1HTR2AKMT2AACKR3
	SCHEMBL1475789	0.84	SIGMAR1 (0.46)	SIGMAR1ALDH1A1MEN1KMT2AACKR3
	SCHEMBL1477207	0.83	ACKR3 (0.32)	ALDH1A1TDP1HTR2AKMT2AACKR3
	SCHEMBL1476158	0.83	ACKR3 (0.34)	ALDH1A1HTR2AACKR3
	SCHEMBL1474926	0.83	SIGMAR1 (0.42)	SIGMAR1ALDH1A1KMT2AACKR3
	SCHEMBL12827515	0.82	L3MBTL1 (0.38)	ALDH1A1HTR2AKMT2AACKR3
	SCHEMBL1474298	0.82	SIGMAR1 (0.46)	SIGMAR1ALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.