Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.53 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.53 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15984778 | 0.88 | POLB (0.59) | POLBL3MBTL1DRD2DRD4TSHR | |
| SCHEMBL29521270 | 0.88 | POLB (0.59) | POLBL3MBTL1DRD2DRD4TSHR | |
| SCHEMBL18763040 | 0.84 | ALDH1A1 (0.67) | POLBL3MBTL1DRD2DRD4TSHR | |
| SCHEMBL11713976 | 0.84 | DRD2 (0.57) | POLBL3MBTL1DRD2DRD4TSHR | |
| SCHEMBL14229139 | 0.83 | MTNR1A (0.48) | POLBL3MBTL1TSHR | |
| SCHEMBL14756045 | 0.82 | DRD2 (0.55) | POLBL3MBTL1DRD2DRD4TSHR | |
| SCHEMBL17018045 | 0.80 | NOTUM (0.71) | POLBL3MBTL1DRD2DRD4TSHR | |
| SCHEMBL30366447 | 0.80 | NOTUM (0.71) | POLBL3MBTL1DRD2DRD4TSHR | |
| SCHEMBL1825815 | 0.80 | NOTUM (0.71) | POLBL3MBTL1DRD2DRD4TSHR | |
| SCHEMBL30366703 | 0.80 | NOTUM (0.71) | POLBL3MBTL1DRD2DRD4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033268-A2 | BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |