SCHEMBL1475717

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1477011	0.92	MAPKAPK5 (1.00)	MAPKAPK5FYNTBK1CDK2CCNE1
	SCHEMBL12443284	0.86	MAPKAPK5 (0.89)	MAPKAPK5TBK1
	SCHEMBL2217522	0.83	MAPKAPK5 (0.83)	MAPKAPK5TBK1
	SCHEMBL1477098	0.83	MAPKAPK5 (0.83)	MAPKAPK5TBK1
	SCHEMBL2221000	0.83	MAPKAPK5 (0.70)	MAPKAPK5FYNCDK2CCNE1
	SCHEMBL2218524	0.83	MAPKAPK5 (0.82)	MAPKAPK5FYNTBK1
	SCHEMBL1477008	0.83	MAPKAPK5 (0.72)	MAPKAPK5FYN
	SCHEMBL1477550	0.82	MAPKAPK5 (0.71)	MAPKAPK5FYNCDK2CCNE1
	SCHEMBL1475077	0.82	MAPKAPK5 (0.81)	MAPKAPK5FYNTBK1CDK2CCNT1
	SCHEMBL1475392	0.82	MAPKAPK5 (0.81)	MAPKAPK5FYNTBK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.