SCHEMBL1476034

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2217497	0.89	MAPKAPK5 (0.71)	MAPKAPK5PTK6LCKAURKBCSF1R
	SCHEMBL2218746	0.84	MAPKAPK5 (0.78)	MAPKAPK5PTK6LCKAURKBLRRK2
	SCHEMBL1475839	0.83	TRPV1 (0.39)	MAPKAPK5CCNA2CDK2CCNA1PIM1
	SCHEMBL1476474	0.82	MAPKAPK5 (0.61)	MAPKAPK5PTK6LCKAURKBLRRK2
	SCHEMBL1478071	0.82	MAPKAPK5 (0.61)	MAPKAPK5CCNA2CDK2CCNA1PIM1
	SCHEMBL12443308	0.81	MAPKAPK5 (0.59)	MAPKAPK5PTK6LCKAURKBLRRK2
	SCHEMBL12443729	0.81	MAPKAPK5 (0.73)	MAPKAPK5PTK6LCKAURKBCDK2
	SCHEMBL3800656	0.80	MAPKAPK5 (0.68)	MAPKAPK5PTK6LCKAURKB
	SCHEMBL1476521	0.77	MAPKAPK5 (0.75)	MAPKAPK5PTK6LCKAURKBCDK4
	SCHEMBL1475927	0.77	MAPKAPK5 (0.61)	MAPKAPK5PTK6LCKAURKBCDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.