Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28812528 | 0.89 | TRPC6 (0.54) | TRPC6 | |
| SCHEMBL14764554 | 0.83 | ALOX5AP (0.39) | TRPC6 | |
| SCHEMBL15174527 | 0.82 | TRPC6 (0.58) | TRPC6 | |
| SCHEMBL30439726 | 0.82 | TRPC6 (0.58) | TRPC6 | |
| SCHEMBL14763960 | 0.82 | GPR119 (0.34) | TRPC6 | |
| SCHEMBL14764299 | 0.81 | DDB1 (0.41) | TRPC6 | |
| SCHEMBL7303971 | 0.80 | SLC18A3 (0.42) | — | |
| SCHEMBL14764325 | 0.79 | GPR119 (0.36) | TRPC6 | |
| SCHEMBL18352270 | 0.78 | TRPC6 (0.53) | TRPC6 | |
| SCHEMBL16376300 | 0.77 | TRPC6 (0.47) | TRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013034238-A1 | BENZONITRILE DERIVATIVES AS KINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2013-03-14 | — | — | WO | disclosed |