Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 3/20 | 0.39 |
| ▸ | FABP7 | O15540 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18170903 | 0.74 | FABP5 (0.44) | FABP5FABP7CA1CA2KMT2A | |
| SCHEMBL5330089 | 0.72 | FABP5 (0.43) | FABP5FABP7CA1CA2KMT2A | |
| SCHEMBL27028193 | 0.72 | PTGES (0.44) | FABP5FABP7KMT2AMEN1 | |
| SCHEMBL27687616 | 0.71 | CA1 (0.45) | FABP5FABP7CA1CA2KMT2A | |
| SCHEMBL289035 | 0.70 | FABP5 (0.40) | FABP5FABP7CA1CA2KMT2A | |
| SCHEMBL4678772 | 0.70 | KMT2A (0.36) | FABP5FABP7CA1CA2KMT2A | |
| SCHEMBL14590853 | 0.69 | FABP5 (0.47) | FABP5FABP7CA1CA2KMT2A | |
| SCHEMBL8587365 | 0.69 | CA1 (0.54) | FABP5FABP7CA1CA2KMT2A | |
| SCHEMBL27577191 | 0.69 | CA1 (0.40) | FABP5FABP7CA1CA2KMT2A | |
| SCHEMBL8451311 | 0.69 | CA1 (0.42) | FABP5FABP7CA1CA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013036749-A1 | HCV HELICASE INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF KANSAS (US) | 2013-03-14 | — | — | WO | disclosed |