Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 3/20 | 0.43 |
| ▸ | FABP7 | O15540 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27028193 | 0.87 | PTGES (0.44) | FABP5FABP7KMT2AMEN1 | |
| SCHEMBL18170903 | 0.85 | FABP5 (0.44) | FABP5FABP7KMT2AALDH1A1EPHX2 | |
| SCHEMBL12155397 | 0.79 | FABP5 (0.48) | FABP5FABP7KMT2AEPHX2CASP3 | |
| SCHEMBL12179757 | 0.79 | FABP5 (0.46) | FABP5FABP7KMT2AEPHX2CASP3 | |
| SCHEMBL12179490 | 0.78 | FABP5 (0.47) | FABP5FABP7KMT2AALDH1A1GLA | |
| SCHEMBL900046 | 0.78 | KMT2A (0.47) | FABP5FABP7KMT2AEPHX2CASP3 | |
| SCHEMBL31758375 | 0.78 | CHRNB2 (0.43) | FABP5FABP7KMT2AALDH1A1EPHX2 | |
| SCHEMBL8011283 | 0.78 | SMN1; SMN2 (0.47) | FABP5FABP7KMT2ATSHREPHX2 | |
| SCHEMBL3812973 | 0.78 | PTGIR (0.43) | FABP5FABP7KMT2AEPHX2CASP3 | |
| SCHEMBL13327270 | 0.77 | KMT2A (0.49) | FABP5FABP7KMT2ATSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144379-A1 | BICYCLIC COMPOUNDS USEFUL AS CATHEPSIN S INBHIBITORS | MEDIVIR AB (SE) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007144379-A1 | BICYCLIC COMPOUNDS USEFUL AS CATHEPSIN S INBHIBITORS | MEDIVIR AB (SE) | 2007-12-21 | — | — | WO | disclosed |
| WO-2006064286-A1 | CATHEPSIN S INHIBITORS | MEDIVIR UK LTD (GB) | 2006-06-22 | — | — | WO | disclosed |
| WO-2006064286-A1 | CATHEPSIN S INHIBITORS | MEDIVIR UK LTD (GB) | 2006-06-22 | — | — | WO | disclosed |