Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | RBP4 | P02753 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.34 |
| ▸ | FABP7 | O15540 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4676067 | 0.80 | HTR2C (0.39) | CA1CA2 | |
| SCHEMBL4678774 | 0.72 | EPHX2 (0.48) | KMT2AOPRD1 | |
| SCHEMBL6605558 | 0.71 | MEN1 (0.47) | KMT2AMEN1RBP4TSHR | |
| SCHEMBL2358709 | 0.71 | FABP5 (0.54) | KMT2AMEN1TSHRFABP5FABP7 | |
| SCHEMBL14764282 | 0.70 | FABP5 (0.39) | KMT2AMEN1FABP5FABP7CA1 | |
| SCHEMBL3219970 | 0.70 | FABP5 (0.49) | KMT2AOPRD1TSHRFABP5FABP7 | |
| SCHEMBL6606751 | 0.70 | MEN1 (0.44) | KMT2AMEN1RBP4 | |
| SCHEMBL4706660 | 0.68 | ALDH1A1 (0.48) | KMT2AMEN1TSHRFABP5FABP7 | |
| SCHEMBL18687757 | 0.67 | L3MBTL1 (0.46) | KMT2AMEN1TSHRFABP5FABP7 | |
| SCHEMBL2101664 | 0.67 | RBP4 (0.47) | KMT2AMEN1RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416933-B8 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEN INC (US) | 2008-08-27 | — | — | EP | disclosed |
| EP-1416933-A1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | Amgem, Inc. (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003009847-A1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM, INC. (US) | 2003-02-06 | — | — | WO | disclosed |