Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14764227 | 0.77 | L3MBTL1 (0.50) | TP53GAAL3MBTL1KMT2AMEN1 | |
| SCHEMBL1496397 | 0.76 | TP53 (0.42) | TP53GAAKMT2AMEN1CXCR1 | |
| SCHEMBL14764443 | 0.76 | ALDH1A1 (0.50) | TP53GAAKMT2AMEN1CXCR1 | |
| SCHEMBL15228630 | 0.76 | ALDH1A1 (0.50) | TP53GAAKMT2AMEN1CXCR1 | |
| SCHEMBL7881974 | 0.74 | ALDH1A1 (0.44) | TP53GAAKMT2AMEN1CXCR1 | |
| SCHEMBL31577354 | 0.74 | ALDH1A1 (0.44) | TP53GAAKMT2AMEN1CXCR1 | |
| SCHEMBL31383892 | 0.73 | KMT2A (0.40) | TP53GAAKMT2AMEN1CXCR1 | |
| SCHEMBL28785699 | 0.73 | TP53 (0.41) | TP53GAAL3MBTL1KMT2AMEN1 | |
| SCHEMBL17268395 | 0.71 | HCAR3 (0.46) | TP53GAAL3MBTL1KMT2AMEN1 | |
| SCHEMBL17269792 | 0.71 | GAA (0.39) | TP53GAAL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013034755-A1 | TRIAZOLOPYRAZINE DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | H. LUNDBECK A/S (DK) | 2013-03-14 | — | — | WO | disclosed |