Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14764293 | 0.77 | TP53 (0.51) | L3MBTL1ATMTP53GAAANPEP | |
| SCHEMBL31722410 | 0.73 | L3MBTL1 (0.46) | L3MBTL1ATMHTTMEN1RAB9A | |
| SCHEMBL6243373 | 0.71 | L3MBTL1 (0.61) | L3MBTL1GAAANPEPHTTRAB9A | |
| SCHEMBL11283093 | 0.71 | ALDH1A1 (0.66) | L3MBTL1GAAANPEPHTTMEN1 | |
| SCHEMBL9850400 | 0.71 | KDM4E (0.59) | L3MBTL1GAAANPEPMEN1RAB9A | |
| SCHEMBL1654361 | 0.71 | EGFR (0.36) | L3MBTL1ATMGAAANPEPLMNA | |
| SCHEMBL6366669 | 0.70 | MAOA (0.62) | L3MBTL1GAAMEN1RAB9AKMT2A | |
| SCHEMBL28063105 | 0.70 | L3MBTL1 (0.55) | L3MBTL1TP53GAAMDM4HTT | |
| SCHEMBL27776940 | 0.70 | ALDH1A1 (0.33) | L3MBTL1ATMTP53GAAANPEP | |
| SCHEMBL13390992 | 0.69 | TP53 (0.65) | L3MBTL1ATMTP53GAAANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013034755-A1 | TRIAZOLOPYRAZINE DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | H. LUNDBECK A/S (DK) | 2013-03-14 | — | — | WO | disclosed |