SCHEMBL1476431

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1475267	0.79	DCPS (0.44)	—
	SCHEMBL1477211	0.79	MAOA (0.51)	HTR2AHTR2CKMT2AATM
	SCHEMBL1475287	0.79	ATM (0.41)	JAK2JAK1TYK2JAK3ATM
	SCHEMBL12827747	0.78	GRM2 (0.47)	JAK2JAK1TYK2JAK3ALDH1A1
	SCHEMBL1476560	0.78	GRIN2B (0.39)	KDM4EKDM5BKDM4BHTR2BKMT2A
	SCHEMBL1475908	0.78	CNR2 (0.36)	JAK2JAK1TYK2JAK3CNR2
	SCHEMBL1476139	0.78	DCPS (0.39)	HTR2CKDM5BHTR2BHTR7
	SCHEMBL1475503	0.78	OPRM1 (0.35)	OPRM1KDM5BKDM4BATMKDM4A
	SCHEMBL1476785	0.78	CTNNB1 (0.38)	KMT2A
	SCHEMBL1476309	0.78	OPRM1 (0.35)	OPRM1HTR2CKDM5BKDM4BHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.