Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.48 |
| ▸ | MMP12 | P39900 | 4/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | MMP14 | P50281 | 3/20 | 0.43 |
| ▸ | MMP16 | P51512 | 3/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079419 | 0.89 | AKR1B1 (0.52) | MMP2MMP12MMP9AKR1B1TDP1 | |
| SCHEMBL14764226 | 0.84 | THRB (0.46) | MMP2MMP12MMP9AKR1B1TDP1 | |
| SCHEMBL12477045 | 0.84 | PTGDR2 (0.47) | MMP2MMP12MMP9AKR1B1TDP1 | |
| SCHEMBL11073817 | 0.82 | AKR1B1 (0.60) | MMP2MMP12MMP9AKR1B1TDP1 | |
| SCHEMBL29639215 | 0.82 | KMT2A (0.54) | TDP1HSD17B10FABP4FABP5STING1 | |
| SCHEMBL991380 | 0.82 | KMT2A (0.54) | TDP1HSD17B10FABP4FABP5STING1 | |
| SCHEMBL14693750 | 0.82 | PTGS2 (0.51) | MMP2MMP12MMP9AKR1B1TDP1 | |
| SCHEMBL836780 | 0.81 | FABP4 (0.56) | MMP2MMP12MMP9AKR1B1TDP1 | |
| Hydrochloric Acid SCHEMBL2532791 | 0.81 | KMT2A (0.55) | TDP1HSD17B10FABP4FABP5STING1 | |
| SCHEMBL2729290 | 0.81 | MEN1 (0.49) | MMP2MMP12MMP9AKR1B1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013034119-A1 | 4-METHYLCATECHOL DERIVATIVES UND USE THEREOF | Thanares GmbH (DE) | 2013-03-14 | — | — | WO | claimed |
| WO-2013034119-A1 | 4-METHYLCATECHOL DERIVATIVES UND USE THEREOF | Thanares GmbH (DE) | 2013-03-14 | — | — | WO | disclosed |