Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251300 | 0.85 | FABP4 (0.58) | THRBFABP4FABP5AKR1B1L3MBTL1 | |
| SCHEMBL14764349 | 0.84 | MMP2 (0.48) | FABP4FABP5AKR1B1TDP1CYP1A2 | |
| SCHEMBL3236664 | 0.83 | CXCL8 (0.50) | THRBFABP4FABP5AKR1B1TDP1 | |
| SCHEMBL7796121 | 0.81 | NR1H4 (0.44) | THRBFABP4FABP5AKR1B1TDP1 | |
| SCHEMBL14764447 | 0.77 | MAPT (0.38) | TDP1L3MBTL1KDM4EMAPTKMT2A | |
| SCHEMBL9079419 | 0.76 | AKR1B1 (0.52) | FABP4FABP5AKR1B1TDP1CYP1A2 | |
| SCHEMBL1628791 | 0.75 | L3MBTL1 (0.62) | FABP4FABP5AKR1B1L3MBTL1GLA | |
| SCHEMBL5120093 | 0.75 | L3MBTL1 (0.53) | FABP4FABP5AKR1B1TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL2525349 | 0.74 | L3MBTL1 (0.61) | AKR1B1L3MBTL1GLAKDM4EMAPT | |
| SCHEMBL8573806 | 0.73 | AKR1B1 (0.64) | AKR1B1TDP1CYP1A2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013034119-A1 | 4-METHYLCATECHOL DERIVATIVES UND USE THEREOF | Thanares GmbH (DE) | 2013-03-14 | — | — | WO | claimed |
| WO-2013034119-A1 | 4-METHYLCATECHOL DERIVATIVES UND USE THEREOF | Thanares GmbH (DE) | 2013-03-14 | — | — | WO | disclosed |