Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | DRD1 | P21728 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21879796 | 0.83 | ALDH1A1 (0.50) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL274249 | 0.80 | CES1 (0.48) | LMNAMAPTALDH1A1TSHRMEN1 | |
| SCHEMBL272999 | 0.78 | CA1 (0.57) | LMNAMAPTMEN1NR1I2MAPK1 | |
| Bromomethane SCHEMBL30082988 | 0.77 | CES1 (0.45) | LMNAMAPTALDH1A1TSHRMEN1 | |
| SCHEMBL30420427 | 0.76 | CA1 (0.55) | LMNAMAPTMEN1NR1I2MAPK1 | |
| Butane SCHEMBL28233321 | 0.71 | PARP10 (0.61) | ESR1ESR2LMNAMAPTALDH1A1 | |
| Butane SCHEMBL27816339 | 0.71 | HSD17B3 (0.57) | ESR1ESR2LMNAMAPTALDH1A1 | |
| Paroxypropione SCHEMBL440470 | 0.70 | HSD17B3 (0.68) | ESR1ESR2LMNAMAPTALDH1A1 | |
| Paraben SCHEMBL1685437 | 0.70 | CA2 (0.80) | ESR1ESR2LMNAMAPTALDH1A1 | |
| Diethylstilbestrol SCHEMBL2440008 | 0.70 | ESR1 (0.78) | ESR1ESR2LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9668946-B2 | Dental materials based on monomers having debonding-on-demand properties | IVOCLAR VIVADENT AG (LI) | 2017-06-06 | — | — | US | disclosed |
| US-20140329929-A1 | DENTAL MATERIALS BASED ON MONOMERS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2014-11-06 | — | — | US | disclosed |
| WO-2013034777-A2 | DENTAL MATERIALS BASED ON MONOMERS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2013-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140329929-A1 | DENTAL MATERIALS BASED ON MONOMERS HAVING DEBONDING-ON-DEMAND PROPERTIES | RCOR3, NR2E1, RER1 | ESR1 490/4885ESR2 189/4885LMNA 3049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.