Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14764362 | 0.93 | MAPT (0.42) | MAPTRAB9AMAPK1ALDH1A1KDM4E | |
| SCHEMBL14764528 | 0.83 | MAPT (0.41) | MAPTRAB9AMAPK1ALDH1A1KDM4E | |
| SCHEMBL14764541 | 0.83 | ALDH1A1 (0.37) | MAPTRAB9AALDH1A1KDM4EPOLB | |
| SCHEMBL14764659 | 0.80 | NQO2 (0.56) | MAPTRAB9AMAPK1ALDH1A1KDM4E | |
| SCHEMBL12503018 | 0.79 | MAPT (0.58) | MAPTRAB9AMAPK1ALDH1A1KDM4E | |
| SCHEMBL8604288 | 0.78 | MAPT (0.52) | MAPTRAB9AMAPK1ALDH1A1KDM4E | |
| SCHEMBL14764633 | 0.76 | MAPT (0.41) | MAPTRAB9AALDH1A1KDM4EPOLB | |
| SCHEMBL14764490 | 0.76 | ALDH1A1 (0.41) | MAPTRAB9AMAPK1ALDH1A1KDM4E | |
| SCHEMBL20475325 | 0.76 | RAB9A (0.53) | MAPTRAB9AMAPK1ALDH1A1POLB | |
| SCHEMBL31643056 | 0.76 | RAB9A (0.53) | MAPTRAB9AMAPK1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013034758-A1 | SUBSTITUTED TRIAZOLOPYRAZINES AND USES THEREOF | H. LUNDBECK A/S (DK) | 2013-03-14 | — | — | WO | disclosed |
| WO-2013034758-A1 | SUBSTITUTED TRIAZOLOPYRAZINES AND USES THEREOF | H. LUNDBECK A/S (DK) | 2013-03-14 | — | — | WO | disclosed |
| WO-2013034755-A1 | TRIAZOLOPYRAZINE DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | H. LUNDBECK A/S (DK) | 2013-03-14 | — | — | WO | disclosed |