Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553185 | 0.87 | USP2 (0.40) | STSMAPTHPGDRAB9AAPOBEC3A | |
| Sulfuric Acid SCHEMBL140508 | 0.87 | USP2 (0.40) | STSMAPTHPGDRAB9AAPOBEC3A | |
| Sulfuric Acid SCHEMBL140509 | 0.87 | USP2 (0.40) | STSMAPTHPGDRAB9AAPOBEC3A | |
| SCHEMBL30505 | 0.82 | HPGD (0.46) | MAPTHPGDRAB9AAPOBEC3AAPOBEC3G | |
| Acetic Acid SCHEMBL145430 | 0.81 | MAPK1 (0.47) | MAPTHPGDRAB9AAPOBEC3AAPOBEC3G | |
| Hydrochloric Acid SCHEMBL152518 | 0.80 | HPGD (0.44) | MAPTHPGDRAB9AAPOBEC3AAPOBEC3G | |
| Bromide SCHEMBL145328 | 0.80 | HPGD (0.44) | MAPTHPGDRAB9AAPOBEC3AAPOBEC3G | |
| Iodide SCHEMBL10670645 | 0.80 | APOBEC3A (0.46) | MAPTHPGDRAB9AAPOBEC3AAPOBEC3G | |
| SCHEMBL1712117 | 0.80 | HPGD (0.44) | MAPTHPGDRAB9AAPOBEC3AAPOBEC3G | |
| Paraquat SCHEMBL3676472 | 0.79 | SLC6A4 (0.48) | APOBEC3AAPOBEC3GPABPC1EIF4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2753620-B1 | NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL | SANDOZ AG (CH) | 2017-02-15 | — | — | EP | disclosed |
| US-9382278-B2 | Process for preparing ceftaroline fosamil | SANDOZ AG (CH) | 2016-07-05 | — | — | US | disclosed |
| US-20160009745-A1 | NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL | SANDOZ AG (CH) | 2016-01-14 | — | — | US | disclosed |
| US-9169239-B2 | Process for preparing ceftaroline fosamil | SANDOZ AG (CH) | 2015-10-27 | — | — | US | disclosed |
| US-20150073138-A1 | NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL | SANDOZ AG (CH) | 2015-03-12 | — | — | US | disclosed |
| WO-2013034718-A1 | NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL | SANDOZ AG (CH) | 2013-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150073138-A1 | NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL | FOS, FOSB, CYP3A7 | STS 1134/4885MAPT 4496/4885HPGD 3071/4885 |
| US-20160009745-A1 | NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL | FOS, FOSB, CYP3A7 | STS 981/4885MAPT 4497/4885HPGD 3453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.