Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.73 |
| ▸ | RAB9A | P51151 | 9/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | CASP3 | P42574 | 1/20 | 0.73 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.73 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.73 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | AR | P10275 | 2/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27894128 | 0.98 | KDM4E (0.71) | KDM4ERAB9AKMT2AMEN1MAPT | |
| SCHEMBL10625602 | 0.89 | KDM4E (0.73) | KDM4ERAB9AKMT2AMEN1MAPT | |
| SCHEMBL27935903 | 0.85 | KDM4E (1.00) | KDM4ERAB9AKMT2AMEN1MAPT | |
| SCHEMBL10715489 | 0.85 | RAB9A (0.67) | KDM4ERAB9AKMT2AMEN1MAPT | |
| SCHEMBL23657508 | 0.79 | KDM4E (0.58) | KDM4ERAB9AKMT2AMEN1MAPT | |
| SCHEMBL12046059 | 0.78 | KDM4E (0.67) | KDM4ERAB9AKMT2AMEN1MAPT | |
| SCHEMBL68135 | 0.78 | KDM4E (1.00) | KDM4ERAB9AKMT2AMEN1MAPT | |
| SCHEMBL13480645 | 0.78 | KDM4E (1.00) | KDM4ERAB9AKMT2AMEN1MAPT | |
| SCHEMBL17336954 | 0.78 | KDM4E (0.61) | KDM4ERAB9AKMT2AMEN1MAPT | |
| SCHEMBL6197194 | 0.78 | KDM4E (0.67) | KDM4ERAB9AKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2753620-B1 | NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL | SANDOZ AG (CH) | 2017-02-15 | — | — | EP | claimed |
| US-20160009745-A1 | NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL | SANDOZ AG (CH) | 2016-01-14 | — | — | US | claimed |
| US-9169239-B2 | Process for preparing ceftaroline fosamil | SANDOZ AG (CH) | 2015-10-27 | — | — | US | claimed |
| US-20150073138-A1 | NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL | SANDOZ AG (CH) | 2015-03-12 | — | — | US | claimed |
| WO-2013034718-A1 | NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL | SANDOZ AG (CH) | 2013-03-14 | — | — | WO | claimed |
| EP-2753620-B1 | NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL | SANDOZ AG (CH) | 2017-02-15 | — | — | EP | disclosed |
| US-9382278-B2 | Process for preparing ceftaroline fosamil | SANDOZ AG (CH) | 2016-07-05 | — | — | US | disclosed |
| US-20160009745-A1 | NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL | SANDOZ AG (CH) | 2016-01-14 | — | — | US | disclosed |
| US-9169239-B2 | Process for preparing ceftaroline fosamil | SANDOZ AG (CH) | 2015-10-27 | — | — | US | disclosed |
| US-20150073138-A1 | NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL | SANDOZ AG (CH) | 2015-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150073138-A1 | NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL | FOS, FOSB, CYP3A7 | KDM4E 1419/4885RAB9A 1527/4885KMT2A 1230/4885 |
| US-20160009745-A1 | NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL | FOS, FOSB, CYP3A7 | KDM4E 758/4885RAB9A 767/4885KMT2A 1544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.