SCHEMBL14765684

SCHEMBL14765684

C=CCCOc1ccc(C2CCC(c3ccc(-c4ccc(OCC)cc4)c(F)c3F)CC2)c(F)c1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 6/20 0.41
FFAR1 O14842 3/20 0.41
PPARD Q03181 2/20 0.33
CAMKK1 Q8N5S9 1/20 0.32
CAMKK2 Q96RR4 1/20 0.32
MGAT2 Q10469 1/20 0.31
SLC6A4 P31645 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
KDM4E B2RXH2 2/20 0.30
ALDH1A1 P00352 2/20 0.30
TDP1 Q9NUW8 1/20 0.30
ALOX5AP P20292 1/20 0.30
FEN1 P39748 1/20 0.30
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14765690 0.94 FFAR4 (0.37) FFAR4FFAR1NPC1LMNARAB9A
SCHEMBL14765798 0.92 FFAR4 (0.39) FFAR4FFAR1ALDH1A1NPC1LMNA
SCHEMBL12733967 0.91 CYP2C9 (0.35) FFAR4FFAR1KDM4EALOX5APFEN1
SCHEMBL14766191 0.90 FFAR4 (0.37) FFAR4FFAR1PPARD
SCHEMBL14766870 0.90 FFAR4 (0.35) FFAR4FFAR1PPARDALOX5APFEN1
SCHEMBL14765816 0.90 FFAR1 (0.37) FFAR4FFAR1PPARDALOX5APFEN1
SCHEMBL14765702 0.90 FFAR4 (0.38) FFAR4FFAR1PPARDCAMKK1CAMKK2
SCHEMBL14765686 0.89 FFAR4 (0.44) FFAR4FFAR1PPARDCAMKK1CAMKK2
SCHEMBL14766820 0.89 FFAR4 (0.35) FFAR4FFAR1MGAT2
SCHEMBL14767290 0.89 FFAR1 (0.38) FFAR4FFAR1PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed