SCHEMBL14765702

SCHEMBL14765702

C=CCOc1ccc(C2CCC(c3ccc(-c4ccc(OCC)cc4)c(F)c3F)CC2)c(F)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 5/20 0.38
FFAR1 O14842 3/20 0.38
MAOB P27338 3/20 0.37
MAPT P10636 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
LMNA P02545 1/20 0.37
NPC1 O15118 1/20 0.35
POLB P06746 1/20 0.35
RAB9A P51151 1/20 0.35
MGAM O43451 3/20 0.34
GAA P10253 3/20 0.34
SI P14410 3/20 0.34
MGAM2 Q2M2H8 3/20 0.34
GYS1 P13807 1/20 0.34
CAMKK1 Q8N5S9 1/20 0.33
CAMKK2 Q96RR4 1/20 0.33
MAOA P21397 2/20 0.32
PPARD Q03181 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14765686 0.91 FFAR4 (0.44) FFAR4FFAR1LMNANPC1RAB9A
SCHEMBL12733966 0.91 LMNA (0.38) FFAR4MAOBMAPTSMN1; SMN2MEN1
SCHEMBL14765684 0.90 FFAR4 (0.41) FFAR4FFAR1LMNANPC1RAB9A
SCHEMBL14766170 0.90 FFAR4 (0.34) FFAR4FFAR1MAOBMAPTSMN1; SMN2
SCHEMBL14766179 0.90 PDE4D (0.37) FFAR4FFAR1MAOBMAPTSMN1; SMN2
SCHEMBL14766544 0.90 NAAA (0.36) FFAR4FFAR1MAOBMAPTSMN1; SMN2
SCHEMBL14766813 0.89 FFAR4 (0.33) FFAR4FFAR1MAOBMAPTSMN1; SMN2
SCHEMBL14767107 0.89 PPARD (0.39) FFAR4FFAR1MAOBMAPTSMN1; SMN2
SCHEMBL14765904 0.89 FFAR4 (0.34) FFAR4FFAR1MAOBMAPTSMN1; SMN2
SCHEMBL12733952 0.88 FFAR4 (0.36) FFAR4FFAR1CAMKK1CAMKK2PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed