Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GYS1 | P13807 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | SI | P14410 | 3/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766773 | 0.94 | FFAR4 (0.37) | NAAAHTR2AFFAR4MAOBMAPT | |
| SCHEMBL12740370 | 0.93 | FFAR4 (0.34) | NAAAHTR2AFFAR4MAOBMAPT | |
| SCHEMBL14766170 | 0.93 | FFAR4 (0.34) | NAAAHTR2AFFAR4MAOBMAPT | |
| SCHEMBL14767021 | 0.92 | NAAA (0.40) | NAAAFFAR4FFAR1ESR1PPARD | |
| SCHEMBL14766870 | 0.91 | FFAR4 (0.35) | NAAAFFAR4FFAR1ESR1PPARD | |
| SCHEMBL12740359 | 0.90 | NAAA (0.36) | NAAAFFAR4FFAR1ESR1 | |
| SCHEMBL14765702 | 0.90 | FFAR4 (0.38) | FFAR4MAOBMAPTSMN1; SMN2MEN1 | |
| SCHEMBL14767034 | 0.90 | HTR2A (0.35) | NAAAHTR2AMAOBMAPTSMN1; SMN2 | |
| SCHEMBL12718988 | 0.89 | ACACA (0.34) | NAAAHTR2AFFAR4MAOBMAPT | |
| SCHEMBL14766813 | 0.88 | FFAR4 (0.33) | HTR2AFFAR4MAOBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |