Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.37 |
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766846 | 0.98 | NAAA (0.38) | FFAR1PPARDNAAARARARARB | |
| SCHEMBL14766989 | 0.95 | NAAA (0.37) | FFAR1PPARDNAAARARARARB | |
| SCHEMBL14766598 | 0.94 | PPARD (0.37) | FFAR1PPARDNAAAFFAR4ALOX5AP | |
| SCHEMBL14767003 | 0.93 | PPARD (0.38) | FFAR1PPARDNAAAFFAR4ALOX5AP | |
| SCHEMBL14766852 | 0.92 | GABRA1 (0.36) | FFAR1PPARDNAAARARARARB | |
| SCHEMBL12740337 | 0.92 | SIGMAR1 (0.40) | FFAR1PPARDNAAAFFAR4SCN9A | |
| SCHEMBL14766954 | 0.92 | GABRA1 (0.35) | FFAR1PPARDNAAARARARARB | |
| SCHEMBL14766567 | 0.90 | PPARD (0.39) | FFAR1PPARDNAAAFFAR4ALOX5AP | |
| SCHEMBL14766979 | 0.90 | FFAR1 (0.41) | FFAR1PPARDNAAAFFAR4DRD4 | |
| SCHEMBL12740338 | 0.89 | SIGMAR1 (0.40) | NAAAFFAR4GABRA1GABRB2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |