Anazolene

Anazolene

SCHEMBL1476742

O=S(=O)(O)c1cc(O)c2c(N=Nc3ccc(Nc4ccccc4)c4c(S(=O)(=O)O)cccc34)cc(S(=O)(=O)O)cc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 1.00
THRB P10828 2/20 1.00
KMT2A Q03164 2/20 1.00
SNCA P37840 3/20 0.55
CHAT P28329 1/20 0.55
CYP1A2 P05177 4/20 0.52
CYP2C9 P11712 3/20 0.52
MAPK1 P28482 2/20 0.52
DNASE1L3 Q13609 1/20 0.52
TTR P02766 1/20 0.52
FABP4 P15090 1/20 0.52
CCNA2 P20248 1/20 0.52
CDK2 P24941 1/20 0.52
MAPK14 Q16539 1/20 0.52
NR4A1 P22736 1/20 0.51
ENPP2 Q13822 1/20 0.50
PRMT1 Q99873 1/20 0.49
NSD2 O96028 1/20 0.48
DUSP3 P51452 1/20 0.48
PTPN5 P54829 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anazolene SCHEMBL29375317 1.00 MEN1 (1.00) MEN1THRBKMT2ASNCACHAT
Anazolene SCHEMBL26460213 1.00 MEN1 (1.00) MEN1THRBKMT2ASNCACHAT
Anazolene SCHEMBL29387597 1.00 MEN1 (1.00) MEN1THRBKMT2ASNCACHAT
Anazolene SCHEMBL11148088 1.00 MEN1 (1.00) MEN1THRBKMT2ASNCACHAT
Anazolene SCHEMBL23595 0.99 MEN1 (0.98) MEN1THRBKMT2ASNCACHAT
SCHEMBL26459262 0.95 MEN1 (0.91) MEN1THRBKMT2ASNCACHAT
Anazolene SCHEMBL1649427 0.87 KMT2A (0.76) MEN1THRBKMT2ASNCACHAT
Anazolene SCHEMBL29374551 0.87 KMT2A (0.76) MEN1THRBKMT2ASNCACHAT
Anazolene SCHEMBL23594 0.87 KMT2A (0.76) MEN1THRBKMT2ASNCACHAT
SCHEMBL12177943 0.83 MEN1 (0.71) MEN1THRBKMT2ASNCACHAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9759733-B1 Mass produced, low cost, portable test kit for the detection and identification of narcotics VERITEQUE USA, INC. 2017-09-12 US claimed
US-4375357-A Water-soluble fast polymeric black colorant, its preparation and use in dyes and inks DYNAPOL (US) 1983-03-01 US claimed
US-9759733-B1 Mass produced, low cost, portable test kit for the detection and identification of narcotics VERITEQUE USA, INC. 2017-09-12 US disclosed
EP-1860158-B1 Particles comprising a substrate and an anion-binding layer MERCK PATENT GMBH (DE) 2013-12-04 EP disclosed
US-7914893-B2 Particles comprising an anion-binding layer containing anion-forming organic active compounds, and method of making and using thereof MERCK PATENT GMBH (DE) 2011-03-29 US disclosed
US-20070275244-A1 Particles MERCK PATENT GMBH 2007-11-29 US disclosed
EP-1860158-A2 Particles comprising a substrate and an anion-binding layer MERCK PATENT GmbH (DE) 2007-11-28 EP disclosed
US-4391894-A BASIC DYE REACTED WITH ORGANIC ACID DISSOLVED IN A PHOTOSENSITIVE DIAZO COMPOSITION POLYCHROME CORPORATION (US) 1983-07-05 US disclosed
US-4375357-A Water-soluble fast polymeric black colorant, its preparation and use in dyes and inks DYNAPOL (US) 1983-03-01 US disclosed