Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Anazolene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | DUSP5 | Q16690 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | CHAT | P28329 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.41 |
| ▸ | PLEC | Q15149 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anazolene SCHEMBL1649427 | 1.00 | KMT2A (0.76) | KMT2AMEN1THRBDUSP5PTPN1 | |
| Anazolene SCHEMBL29374551 | 1.00 | KMT2A (0.76) | KMT2AMEN1THRBDUSP5PTPN1 | |
| Anazolene SCHEMBL26460213 | 0.87 | MEN1 (1.00) | KMT2AMEN1THRBCHATSNCA | |
| Anazolene SCHEMBL1476742 | 0.87 | MEN1 (1.00) | KMT2AMEN1THRBCHATSNCA | |
| Anazolene SCHEMBL11148088 | 0.87 | MEN1 (1.00) | KMT2AMEN1THRBCHATSNCA | |
| Anazolene SCHEMBL29375317 | 0.87 | MEN1 (1.00) | KMT2AMEN1THRBCHATSNCA | |
| Anazolene SCHEMBL29387597 | 0.87 | MEN1 (1.00) | KMT2AMEN1THRBCHATSNCA | |
| Anazolene SCHEMBL23595 | 0.86 | MEN1 (0.98) | KMT2AMEN1THRBCHATSNCA | |
| SCHEMBL26459262 | 0.83 | MEN1 (0.91) | KMT2AMEN1THRBCHATSNCA | |
| SCHEMBL11112899 | 0.82 | KMT2A (0.56) | KMT2AMEN1THRBDUSP5PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 86704 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4732029-A1 | METHODS FOR MAGNETIC RESONANCE MOLECULAR IMAGING OF NANOCONSTRUCTS AND USES THEREOF | Regents of the University of Michigan (US) | 2026-04-29 | — | — | EP | claimed |
| US-20250272996-A1 | SYSTEMS AND METHODS FOR EVALUATING BIOLOGICAL SAMPLES | 10X GENOMICS, INC. | 2025-08-28 | — | — | US | claimed |
| US-20250224314-A1 | DEVICE FOR TISSUE SECTION IMMOBILIZATION AND RETENTION | Singular Genomics Systems, Inc. | 2025-07-10 | — | — | US | claimed |
| WO-2025133616-A1 | CONJUGATED POLYMER NANOPARTICLE BIOSENSORS | STREAM BIO LTD (GB) | 2025-06-26 | — | — | WO | claimed |
| EP-4565870-A1 | SYSTEMS AND METHODS FOR IMMUNOFLUORESCENCE QUANTIFICATION | 10x Genomics, Inc. (US) | 2025-06-11 | — | — | EP | claimed |
| US-20250179475-A1 | METHODS FOR REDUCING CAPTURE OF ANALYTES | 10X GENOMICS, INC. | 2025-06-05 | — | — | US | claimed |
| US-12295811-B2 | Ligature device and method of use | Chinook Contract Research Inc. (CA) | 2025-05-13 | — | — | US | claimed |
| WO-2025089973-A1 | ARTIFICIAL PROTEIN SENSOR FOR PROTEASE ACTIVITY AND INHIBITION | UNIVERSIDAD PERUANA DE CIENCIAS APLICADAS S.A.C. (PE) | 2025-05-01 | — | — | WO | claimed |
| CN-119846233-A | FXR interaction protein analysis strategy based on dual ligand driving and application thereof | 中国药科大学 | 2025-04-18 | — | — | CN | claimed |
| WO-2025048653-A1 | ANALYTICAL METHODS AND RELATED COMPOSITIONS AND USES | OTAGO INNOVATION LIMITED (NZ) | 2025-03-06 | — | — | WO | claimed |
| US-4755460-A | Bovine antigen glycoprotein, related antibody, and use in detection of pregnancy in cattle | THE REGENTS OF THE UNIV. OF MINNESOTA (US) | 1988-07-05 | — | — | US | claimed |
| EP-0243448-A1 | TEST FOR INTESTINAL POLYPS | UNIVERSITY OF FLORIDA (US) | 1987-11-04 | — | — | EP | claimed |
| US-4696896-A | Gonococcal Pili processes for the preparation thereof and the use thereof for the detection of and prevention of infections caused by Neisseria gonorrhoeae | BACTEX, INC. (US) | 1987-09-29 | — | — | US | claimed |
| WO-1987002463-A1 | TEST FOR INTESTINAL POLYPS | FLORIDA ATLANTIC UNIVERSITY (US) | 1987-04-23 | — | — | WO | claimed |
| EP-0188551-A1 | BOVINE ANTIGEN GLYCOPROTEIN, RELATED ANTIBODY, AND USE IN DETECTION OF PREGNANCY IN CATTLE | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1986-07-30 | — | — | EP | claimed |
| WO-1986000623-A1 | BOVINE ANTIGEN GLYCOPROTEIN, RELATED ANTIBODY, AND USE IN DETECTION OF PREGNANCY IN CATTLE | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1986-01-30 | — | — | WO | claimed |
| US-4460694-A | Bovine glycoproteins and use in diagnosing infectious mononucleosis | UNIVERSITY OF MIAMI (US) | 1984-07-17 | — | — | US | claimed |
| US-4459356-A | Radioactive staining of gels to identify proteins | GEORGETOWN UNIVERSITY (US) | 1984-07-10 | — | — | US | claimed |
| EP-0061912-A2 | New purified glycoproteins from cow, horse and sheep and use in diagnosing infectious mononucleosis | UNIVERSITY OF MIAMI (US) | 1982-10-06 | — | — | EP | claimed |
| US-4158049-A | GRINDING, CHROMATOGRAPHY, ELUTION | EDNA MCCONNELL CLARK FOUNDATION (US) | 1979-06-12 | — | — | US | claimed |