Anazolene

Anazolene

SCHEMBL29375317

O=S(=O)(O)c1cc(O)c2c(N=Nc3ccc(Nc4ccccc4)c4c(S(=O)(=O)O)cccc34)cc(S(=O)(=O)O)cc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 1.00
THRB P10828 2/20 1.00
KMT2A Q03164 2/20 1.00
SNCA P37840 3/20 0.55
CHAT P28329 1/20 0.55
CYP1A2 P05177 4/20 0.52
CYP2C9 P11712 3/20 0.52
MAPK1 P28482 2/20 0.52
DNASE1L3 Q13609 1/20 0.52
TTR P02766 1/20 0.52
FABP4 P15090 1/20 0.52
CCNA2 P20248 1/20 0.52
CDK2 P24941 1/20 0.52
MAPK14 Q16539 1/20 0.52
NR4A1 P22736 1/20 0.51
ENPP2 Q13822 1/20 0.50
PRMT1 Q99873 1/20 0.49
NSD2 O96028 1/20 0.48
DUSP3 P51452 1/20 0.48
PTPN5 P54829 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anazolene SCHEMBL26460213 1.00 MEN1 (1.00) MEN1THRBKMT2ASNCACHAT
Anazolene SCHEMBL29387597 1.00 MEN1 (1.00) MEN1THRBKMT2ASNCACHAT
Anazolene SCHEMBL1476742 1.00 MEN1 (1.00) MEN1THRBKMT2ASNCACHAT
Anazolene SCHEMBL11148088 1.00 MEN1 (1.00) MEN1THRBKMT2ASNCACHAT
Anazolene SCHEMBL23595 0.99 MEN1 (0.98) MEN1THRBKMT2ASNCACHAT
SCHEMBL26459262 0.95 MEN1 (0.91) MEN1THRBKMT2ASNCACHAT
Anazolene SCHEMBL1649427 0.87 KMT2A (0.76) MEN1THRBKMT2ASNCACHAT
Anazolene SCHEMBL29374551 0.87 KMT2A (0.76) MEN1THRBKMT2ASNCACHAT
Anazolene SCHEMBL23594 0.87 KMT2A (0.76) MEN1THRBKMT2ASNCACHAT
SCHEMBL12177943 0.83 MEN1 (0.71) MEN1THRBKMT2ASNCACHAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080209-A Anti-CTLA-4 binding proteins and methods of use thereof 2026-05-26 CN disclosed
US-12622969-B2 Methods for treatment using anti-α4β7 antibody TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-05-12 US disclosed
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN UNIV CALIFORNIA (US) 2026-05-07 US disclosed
US-12606836-B2 Process for extracellular secretion of Brazzein MAGELLAN LIFE SCIENCES LTD. (GB) 2026-04-21 US disclosed
US-12606596-B2 Self-assembling insect ferritin nanoparticles THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2026-04-21 US disclosed
US-12582702-B2 Methods for improving leptin sensitivity for the treatment of obesity and diabetes UNIVERSITY OF MASSACHUSETTS (US) 2026-03-24 US disclosed
US-12544445-B2 Methods for treatment using anti-α4β7 antibody TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-02-10 US disclosed
US-12540198-B2 Antigen-binding polypeptide constructs comprising kappa and lambda light chains and uses thereof ZYMEWORKS BC INC. (CA) 2026-02-03 US disclosed
US-12516371-B2 Msp nanopores and related methods UNIVERSITY OF WASHINGTON (US) 2026-01-06 US disclosed
US-20250387464-A1 RECOMBINANT METAPNEUMOVIRUS F PROTEINS AND THEIR USE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH & HUMAN SERVICES (US) 2025-12-25 US disclosed
CN-107849126-B Heavy chain-only anti-ANG-2 antibodies 阿勒根公司 2022-04-08 CN disclosed
US-20220098286-A1 NEUTRALIZING ANTIBODIES TO HIV-1 GP41 AND THEIR USE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) 2022-03-31 US disclosed
US-11286293-B2 Engineered immunoglobulin heavy chain-light chain pairs and uses thereof ZYMEWORKS, INC. (CA) 2022-03-29 US disclosed
WO-2022058764-A1 SKIN PATCH TEST FOR THE DIAGNOSIS OF IMMUNOLOGICAL PROTECTION AGAINST SARS-COV-2 VIRUS INFECTION SEMMELWEIS EGYETEM (HU) 2022-03-24 WO disclosed
US-20220073963-A1 COMPOSITIONS AND METHODS FOR DETECTING AND TREATING TYPE 1 DIABETES AND OTHER AUTOIMMUNE DISEASES UNIV JOHNS HOPKINS (US) 2022-03-10 US disclosed
US-20220064298-A1 COMPOSITIONS AND METHODS RELATED TO ENGINEERED Fc-ANTIGEN BINDING DOMAIN CONSTRUCTS TARGETED TO CTLA-4 MOMENTA PHARMACEUTICALS, INC. 2022-03-03 US disclosed
US-20220064323-A1 Therapeutic Anti-CD9 Antibody KLING BIOTHERAPEUTICS B.V. (NL) 2022-03-03 US disclosed
US-20220049019-A1 COMPOSITIONS AND METHODS RELATED TO ENGINEERED Fc CONSTRUCTS MOMENTA PHARMACEUTICALS, INC. 2022-02-17 US disclosed
US-20220043001-A1 METHODS AND COMPOSITIONS FOR DETECTING MISFOLDED PROTEINS YALE UNIVERSITY (US) 2022-02-10 US disclosed
EP-3950852-A1 AQUEOUS INK COMPOSITION FOR WRITING INSTRUMENTS MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2022-02-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540198-B2 Antigen-binding polypeptide constructs comprising kappa and lambda light chains and uses thereof CLTB, CLTC, CLTA MEN1 3118/4885THRB 169/4885KMT2A 282/4885
US-20250387464-A1 RECOMBINANT METAPNEUMOVIRUS F PROTEINS AND THEIR USE METTL16, UPF1, SET MEN1 475/4885THRB 1977/4885KMT2A 2591/4885
US-12582702-B2 Methods for improving leptin sensitivity for the treatment of obesity and diabetes ADIPOR1, ADIPOR2, GLP1R MEN1 2384/4885THRB 19/4885KMT2A 969/4885
US-12606596-B2 Self-assembling insect ferritin nanoparticles FTH1, TFRC, FEM1B MEN1 2086/4885THRB 483/4885KMT2A 1592/4885
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN GLP1R, ALB, GIPR MEN1 3545/4885THRB 774/4885KMT2A 2734/4885
US-12544445-B2 Methods for treatment using anti-α4β7 antibody ITGA4, ITGB7, VSIG8 MEN1 4740/4885THRB 481/4885KMT2A 1672/4885
US-12606836-B2 Process for extracellular secretion of Brazzein HM13, SPPL2A, SPPL2B MEN1 2603/4885THRB 880/4885KMT2A 4492/4885
US-12622969-B2 Methods for treatment using anti-α4β7 antibody ITGA4, ITGB7, ITGAV MEN1 4819/4885THRB 446/4885KMT2A 980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.