Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | YWHAG | P61981 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14768415 | 0.88 | GAA (0.48) | ALDH1A1MAPK1L3MBTL1YWHAGLMNA | |
| SCHEMBL14768427 | 0.82 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1TDP1PPARGPPARA | |
| SCHEMBL28209720 | 0.82 | ALDH1A1 (0.69) | ALDH1A1MAPK1L3MBTL1ENPP2YWHAG | |
| SCHEMBL15199298 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1ENPP2TDP1 | |
| SCHEMBL6081043 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL14793687 | 0.78 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1ENPP2YWHAG | |
| SCHEMBL16366586 | 0.78 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1ENPP2YWHAG | |
| SCHEMBL6080931 | 0.77 | ALDH1A1 (0.67) | ALDH1A1MAPK1L3MBTL1ENPP2TDP1 | |
| SCHEMBL14768424 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1PTGDR2ALOX5 | |
| SCHEMBL6784181 | 0.76 | ALDH1A1 (0.96) | ALDH1A1MAPK1L3MBTL1ENPP2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013034756-A1 | BIPHENYL COMPOUNDS FOR USE IN TREATING MALARIA AND OTHER PARASITIC DISORDERS | MEDIZINISCHE HOCHSCHULE HANNOVER (DE) | 2013-03-14 | — | — | WO | disclosed |