Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14768432 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2AKR1B1 | |
| SCHEMBL17130187 | 0.81 | L3MBTL1 (0.52) | ALDH1A1KMT2AMEN1HPGDKDM4E | |
| SCHEMBL14768415 | 0.76 | GAA (0.48) | ALDH1A1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL17124771 | 0.76 | L3MBTL1 (0.47) | ALDH1A1KMT2AMEN1HPGDKDM4E | |
| SCHEMBL14560472 | 0.73 | APP (0.57) | KDM4EFFAR1AKR1B1EPHX1 | |
| SCHEMBL8400366 | 0.71 | EPHX1 (0.51) | ALDH1A1KMT2AMEN1HPGDKDM4E | |
| SCHEMBL11628754 | 0.70 | MEN1 (0.45) | ALDH1A1KMT2AMEN1MAPTATM | |
| SCHEMBL28535379 | 0.70 | FFAR1 (0.59) | KMT2AMEN1HPGDKDM4EMCL1 | |
| SCHEMBL21076155 | 0.70 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4ETSHRMAPT | |
| SCHEMBL3044895 | 0.69 | CASP1 (0.62) | ALDH1A1KMT2AMEN1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013034756-A1 | BIPHENYL COMPOUNDS FOR USE IN TREATING MALARIA AND OTHER PARASITIC DISORDERS | MEDIZINISCHE HOCHSCHULE HANNOVER (DE) | 2013-03-14 | — | — | WO | disclosed |