Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | YWHAG | P61981 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14768432 | 0.88 | ALDH1A1 (0.56) | KMT2AYWHAGALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL13932524 | 0.77 | ALDH1A1 (0.66) | GAAKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL14768427 | 0.76 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL21076155 | 0.75 | ALDH1A1 (0.55) | GAAPOLBYWHAGALDH1A1GFER | |
| SCHEMBL24270333 | 0.73 | L3MBTL1 (0.50) | GAAKMT2AMEN1POLBYWHAG | |
| SCHEMBL9880917 | 0.71 | L3MBTL1 (0.79) | GAAKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL29169367 | 0.71 | L3MBTL1 (0.79) | GAAKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL14768426 | 0.71 | GAA (0.70) | GAAKMT2AMEN1POLBYWHAG | |
| SCHEMBL11633043 | 0.70 | L3MBTL1 (0.53) | GAAKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL23134309 | 0.70 | L3MBTL1 (0.56) | GAAKMT2AMEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013034756-A1 | BIPHENYL COMPOUNDS FOR USE IN TREATING MALARIA AND OTHER PARASITIC DISORDERS | MEDIZINISCHE HOCHSCHULE HANNOVER (DE) | 2013-03-14 | — | — | WO | disclosed |