Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13392637 | 0.96 | TYR (0.36) | ALDH1A1KMT2ATYRLMNAKDM4E | |
| SCHEMBL29336019 | 0.89 | TYR (0.32) | ALDH1A1KMT2ATYRLMNAMAPT | |
| SCHEMBL19760409 | 0.83 | TYR (0.38) | ALDH1A1KMT2ATYRLMNASMN1; SMN2 | |
| SCHEMBL21894643 | 0.79 | ANPEP (0.36) | ALDH1A1KMT2ATYRLMNAMEN1 | |
| SCHEMBL15831118 | 0.78 | THRB (0.40) | ALDH1A1KMT2ATYRPTK2BLMNA | |
| SCHEMBL27396377 | 0.77 | TYR (0.38) | ALDH1A1KMT2ATYRMAPK1MEN1 | |
| SCHEMBL1618270 | 0.77 | ALDH1A1 (0.42) | ALDH1A1KMT2ATYRGAAMAPK1 | |
| SCHEMBL26277706 | 0.77 | TDP1 (0.36) | ALDH1A1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL19654081 | 0.76 | PKM (0.37) | ALDH1A1TYRGLRA1POLB | |
| SCHEMBL16804943 | 0.76 | PKM (0.37) | ALDH1A1TYRGLRA1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230292746-A1 | MIXTURES AND COMPOSITIONS COMPRISING 5-FLUORO-4-IMINO-3- METHYL-1-TOSYL-3,4-DIHYDROPYRIMIDIN-2-ONE, AND METHODS OF USE THEREOF | ADAMA MAKHTESHIM LTD. (IL) | 2023-09-21 | — | — | US | disclosed |
| US-8883880-B2 | Soluble shell polymer composition and method for its preparation | ROHM AND HAAS COMPANY (US) | 2014-11-11 | — | — | US | disclosed |
| US-20130066005-A1 | SOLUBLE SHELL POLYMER COMPOSITION AND METHOD FOR ITS PREPARATION | ROHM AND HAAS COMPANY | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230292746-A1 | MIXTURES AND COMPOSITIONS COMPRISING 5-FLUORO-4-IMINO-3- METHYL-1-TOSYL-3,4-DIHYDROPYRIMIDIN-2-ONE, AND METHODS OF USE THEREOF | CYP3A5, CYP4B1, CYP51A1 | ALDH1A1 352/4885KMT2A 1539/4885TYR 565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.