Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | NPC1 | O15118 | 4/20 | 0.72 |
| ▸ | TP53 | P04637 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855370 | 0.84 | RAB9A (1.00) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| Phenindione SCHEMBL33831 | 0.75 | MAPT (1.00) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| Phenindione SCHEMBL29388073 | 0.75 | MAPT (1.00) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| Phenindione SCHEMBL1443973 | 0.73 | MAPT (0.95) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL10559114 | 0.73 | MAPT (0.95) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| Phenindione SCHEMBL6827577 | 0.73 | MAPT (0.95) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL6274633 | 0.73 | RAB9A (0.76) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| Phenindione SCHEMBL16782144 | 0.71 | MAPT (0.91) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL21048546 | 0.69 | MAPT (0.62) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL14940174 | 0.68 | MAPT (0.63) | RAB9AMAPTNPC1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470075-B2 | Tetratopic phenyl compounds, related metal-organic framework materials and post-assembly elaboration | NORTHWESTERN UNIVERSITY (US) | 2013-06-25 | — | — | US | disclosed |
| US-20130061752-A1 | Tetratopic Phenyl Compounds, Related Metal-Organic Framework Materials and Post-Assembly Elaboration | NORTHWESTERN UNIVERSITY (US) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130061752-A1 | Tetratopic Phenyl Compounds, Related Metal-Organic Framework Materials and Post-Assembly Elaboration | TPR, FABP7, PAICS | RAB9A 4031/4885MAPT 206/4885NPC1 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.