Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.76 |
| ▸ | MAPT | P10636 | 7/20 | 0.76 |
| ▸ | NPC1 | O15118 | 7/20 | 0.76 |
| ▸ | TP53 | P04637 | 4/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.76 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855370 | 0.87 | RAB9A (1.00) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL1114899 | 0.76 | RAB9A (0.47) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL14768931 | 0.73 | RAB9A (0.72) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL6081740 | 0.70 | RAB9A (0.43) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| Phenindione SCHEMBL33831 | 0.69 | MAPT (1.00) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| Phenindione SCHEMBL29388073 | 0.69 | MAPT (1.00) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL6607855 | 0.69 | MAPT (0.65) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL11397716 | 0.69 | MAPT (0.61) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL30568013 | 0.69 | MAPT (0.61) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL10559114 | 0.68 | MAPT (0.95) | RAB9AMAPTNPC1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608371-A1 | PROCESS FOR THE PREPARATION OF DONEPEZIL AND DERIVATIVES THEREOF | RANBAXY LABORATORIES, LTD. (IN) | 2005-12-28 | — | — | EP | claimed |
| WO-2004082685-A1 | PROCESS FOR THE PREPARATION OF DONEPEZIL AND DERIVATIVES THEREOF | RANBAXY LABORATORIES LIMITED (IN) | 2004-09-30 | — | — | WO | claimed |
| EP-1608371-A1 | PROCESS FOR THE PREPARATION OF DONEPEZIL AND DERIVATIVES THEREOF | RANBAXY LABORATORIES, LTD. (IN) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004082685-A1 | PROCESS FOR THE PREPARATION OF DONEPEZIL AND DERIVATIVES THEREOF | RANBAXY LABORATORIES LIMITED (IN) | 2004-09-30 | — | — | WO | disclosed |
| EP-0711756-B1 | Process for the production of benzyl-piperidylmethyl-indanone | BAYER AG (DE) | 1998-07-22 | — | — | EP | disclosed |
| US-5606064-A | Process for the preparation of benzyl-piperidylmethyl-indanones | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-25 | — | — | US | disclosed |
| EP-0711756-A1 | Process for the production of benzyl-piperidylmethyl-indanone | BAYER AG (DE) | 1996-05-15 | — | — | EP | disclosed |