Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10222582 | 1.00 | GAA (0.66) | GAAOPRD1CYP3A4CYP2D6MAPT | |
| SCHEMBL12588948 | 0.86 | GAA (0.48) | GAAOPRD1CYP3A4CYP2D6OPRM1 | |
| SCHEMBL2150392 | 0.86 | GAA (0.48) | GAAOPRD1CYP3A4CYP2D6MRGPRX2 | |
| SCHEMBL12006858 | 0.82 | GAA (0.47) | GAAOPRD1CYP3A4CYP2D6MAPT | |
| SCHEMBL4127868 | 0.82 | GAA (0.47) | GAAOPRD1CYP3A4CYP2D6MAPT | |
| SCHEMBL11263235 | 0.82 | GAA (0.47) | GAAOPRD1CYP3A4CYP2D6MAPT | |
| SCHEMBL11263244 | 0.82 | GAA (0.47) | GAAOPRD1CYP3A4CYP2D6MAPT | |
| SCHEMBL12013632 | 0.82 | GAA (0.47) | GAAOPRD1CYP3A4CYP2D6MAPT | |
| SCHEMBL12960706 | 0.82 | GAA (0.47) | GAAOPRD1CYP3A4CYP2D6MAPT | |
| SCHEMBL10994109 | 0.82 | SLC22A1 (0.43) | GAAOPRD1CYP3A4CYP2D6OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8624031-B2 | Production of alkaloids without the isolation of intermediates | MALLINCKRODT LLC (US) | 2014-01-07 | — | — | US | disclosed |
| US-8624031-B2 | Production of alkaloids without the isolation of intermediates | MALLINCKRODT LLC (US) | 2014-01-07 | — | — | US | disclosed |
| US-20130066080-A1 | Production of Alkaloids without the Isolation of Intermediates | MALLINCKRODT LLC (US) | 2013-03-14 | — | — | US | disclosed |
| US-20130066080-A1 | Production of Alkaloids without the Isolation of Intermediates | MALLINCKRODT LLC (US) | 2013-03-14 | — | — | US | disclosed |
| WO-2013036729-A1 | PRODUCTION OF ALKALOIDS WITHOUT THE ISOLATION OF INTERMEDIATES | MALLINCKRODT LLC (US) | 2013-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130066080-A1 | Production of Alkaloids without the Isolation of Intermediates | CIAPIN1, DHPS, PNMT | GAA 2287/4885OPRD1 2374/4885CYP3A4 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.