Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL1476918

O=S(=O)([O-])C(F)(F)F.O[n+]1ccccc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.38
KCNH2 Q12809 8/20 0.33
ACHE P22303 6/20 0.33
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL31114401 0.79 GPR3 (0.39) GPR3KCNH2ACHEPTPN1
Trifluoromethanesulfonic Acid SCHEMBL65052 0.79 GPR3 (0.39) GPR3KCNH2ACHEPTPN1
Trifluoromethanesulfonic Acid SCHEMBL321089 0.77 KCNH2 (0.40) GPR3KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL29059560 0.77 GPR3 (0.38) GPR3KCNH2ACHEPTPN1
Trifluoromethanesulfonic Acid SCHEMBL10579458 0.77 GPR3 (0.48) GPR3KCNH2ACHEPTPN1
Trifluoromethanesulfonic Acid SCHEMBL29642024 0.77 GPR3 (0.48) GPR3KCNH2ACHEPTPN1
Trifluoromethanesulfonic Acid SCHEMBL596729 0.77 GPR3 (0.48) GPR3KCNH2ACHEPTPN1
Trifluoromethanesulfonic Acid SCHEMBL160986 0.77 GPR3 (0.48) GPR3KCNH2ACHEPTPN1
Trifluoromethanesulfonic Acid SCHEMBL8493995 0.76 KCNH2 (0.39) GPR3KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL9655566 0.76 GPR3 (0.37) GPR3KCNH2ACHEPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8580992-B1 Compounds and methods of arylmethylation (benzylation) as protection for alcohol groups during chemical synthesis The Florida State University Research Foundation, Inc. (US) 2013-11-12 US disclosed
US-8334414-B2 Compounds and methods of arylmethylation (benzylation) as protection for alcohol groups during chemical synthesis FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2012-12-18 US disclosed
US-8008531-B2 Compounds and methods of arylmethylation (benzylation) as protection for alcohol groups during chemical synthesis The Florida State University Research Foundation, Inc. (US) 2011-08-30 US disclosed
US-7915437-B2 Compounds and methods of arylmethylation (benzylation) as protection for alcohol groups during chemical synthesis FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2011-03-29 US disclosed
US-20100324324-A1 Compounds and Methods of Arylmethylation (Benzylation) As Protection For Alcohol Groups During Chemical Synthesis DUDLEY GREGORY 2010-12-23 US disclosed
US-20100324323-A1 Compounds and Methods of Arylmethylation (Benzylation) As Protection For Alcohol Groups During Chemical Synthesis DUDLEY GREGORY 2010-12-23 US disclosed
US-20100256383-A1 Compounds and Methods of Arylmethylation (Benzylation) As Protection For Alcohol Groups During Chemical Synthesis DUDLEY GREGORY 2010-10-07 US disclosed
US-7754909-B1 Compounds and methods of arylmethylation (benzylation) as protection for alcohol groups during chemical synthesis The Florida State University Research Foundation, Inc. (US) 2010-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100324323-A1 Compounds and Methods of Arylmethylation (Benzylation) As Protection For Alcohol Groups During Chemical Synthesis ADH1C, ADH1A, CYP2E1 GPR3 3107/4885KCNH2 2198/4885ACHE 3990/4885
US-20100324324-A1 Compounds and Methods of Arylmethylation (Benzylation) As Protection For Alcohol Groups During Chemical Synthesis ADH1C, ADH1A, CYP2E1 GPR3 3107/4885KCNH2 2198/4885ACHE 3990/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.