Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL65052

F[n+]1ccccc1.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.39
KCNH2 Q12809 10/20 0.34
ACHE P22303 6/20 0.34
PTPN1 P18031 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL31114401 1.00 GPR3 (0.39) GPR3KCNH2ACHEPTPN1
SCHEMBL8714768 0.84
Trifluoromethanesulfonic Acid SCHEMBL8469662 0.84 KCNH2 (0.35) GPR3KCNH2ACHEPTPN1
Trifluoromethanesulfonic Acid SCHEMBL28565076 0.81 ALDH1A1 (0.37) PTPN1
SCHEMBL9174215 0.80 NPSR1 (0.35)
Trifluoromethanesulfonic Acid SCHEMBL1476918 0.79 GPR3 (0.38) GPR3KCNH2ACHEPTPN1
Trifluoromethanesulfonic Acid SCHEMBL29059560 0.79 GPR3 (0.38) GPR3KCNH2ACHEPTPN1
Trifluoromethanesulfonic Acid SCHEMBL321089 0.79 KCNH2 (0.40) GPR3KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL10579458 0.79 GPR3 (0.48) GPR3KCNH2ACHEPTPN1
Trifluoromethanesulfonic Acid SCHEMBL160986 0.79 GPR3 (0.48) GPR3KCNH2ACHEPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 940 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559514-B2 Synthesis of fluorinated nucleotides MERCK SHARP & DOHME LLC (US) 2026-02-24 US claimed
US-12506011-B2 Methods for wet atomic layer etching of transition metal oxide dielectric materials TOKYO ELECTRON LIMITED (JP) 2025-12-23 US claimed
EP-4457212-B1 METHOD FOR PREPARING IONIC COMPOUNDS FUNDACION CENTRO DE INVESTIG COOPERATIVA DE ENERGIAS ALTERNATIVAS CIC ENERGIGUNE FUNDAZIOA (ES) 2025-12-10 EP claimed
WO-2025245089-A1 PROCESSES FOR PREPARING TETRALIN COMPOUNDS ARCUS BIOSCIENCES, INC. (US) 2025-11-27 WO claimed
WO-2025244956-A1 METHODS OF MANUFACTURING DANICAMTIV MyoKardia, Inc. (US) 2025-11-27 WO claimed
EP-3504221-B1 NOVEL PROCESS FOR PREPARATION OF CORTICOSTEROIDS CORAL DRUGS PVT LTD (IN) 2025-11-26 EP claimed
US-20250201572-A1 METHODS FOR WET ATOMIC LAYER ETCHING OF TRANSITION METAL OXIDE DIELECTRIC MATERIALS TOKYO ELECTRON LIMITED (JP) 2025-06-19 US claimed
US-20250066294-A1 METHOD FOR PREPARING IONIC COMPOUNDS FUNDACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA DE ENERGÍAS ALTERNATIVAS CIC ENERGIGUNE FUNDAZIOA (ES) 2025-02-27 US claimed
US-12145901-B1 Process for preparing tetralin compounds ARCUS BIOSCIENCES, INC. (US) 2024-11-19 US claimed
US-11873289-B2 Pyrazole compounds and preparation thereof MyoKardia, Inc. (US) 2024-01-16 US claimed
WO-2004016634-A1 Novel 11,12-Substituted Lactone Ketolide Derivatives Having Antibacterial Activity ENANTA PHARMACEUTICALS, INC. (US) 2004-02-26 WO claimed
US-20030162959-A1 Method for the preparation of 6alpha-fluoro corticosteroids TARO PHARMACEUTICALS U.S.A., INC. 2003-08-28 US claimed
WO-2003047329-A2 METHOD FOR THE PREPARATION OF 6-ALPHA-FLUORO CORTICOSTEROIDS TARO PHARMACEUTICALS U.S.A., INC. (US) 2003-06-12 WO claimed
US-6365246-B1 SOLUTION OR SLURRY SOLVENT ABSORBS HEAT OF VAPORIZATION FOR STABILITY OF QUATERNARY NITROGEN COMPOUNDS SUCH AS 1-CHLOROMETHYL-4-FLUORO-1,4-DIAZONIABICYCLO(2.2.2)OCTANE BIS(TETRAFLUOROBORATE) AIR PRODUCTS AND CHEMICALS, INC. 2002-04-02 US claimed
US-6124269-A NOVEL ERYTHROMYCIN DERIVATIVE ANTIBIOTIC EFFECTIVE AGAINST GRAM-NEGATIVE BACTERIA AND HAVING LESS POTENTIAL FOR DEVELOPING BACTERIAL DRUG RESISTANCE ABBOTT LABORATORIES (US) 2000-09-26 US claimed
EP-1027362-A1 2-HALO-6-O-SUBSTITUTED KETOLIDE DERIVATIVES Abbott Laboratories (US) 2000-08-16 EP claimed
EP-0992494-A1 Package for safe storage of electrophilic fluorinating agent AIR PRODUCTS AND CHEMICALS, INC. (US) 2000-04-12 EP claimed
WO-1999021871-A1 2-HALO-6-O-SUBSTITUTED KETOLIDE DERIVATIVES ABBOTT LABORATORIES (US) 1999-05-06 WO claimed
US-5897940-A Ink jet transparencies XEROX CORPORATION (US) 1999-04-27 US claimed
US-5336772-A Reacting pyridine compound, fluorine and Bronsted acid in specified ratios ONODA CEMENT CO., LTD. (JP) 1994-08-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11873289-B2 Pyrazole compounds and preparation thereof TNNI3, TNNT2, HNRNPL GPR3 2290/4885KCNH2 5/4885ACHE 4533/4885
US-12145901-B1 Process for preparing tetralin compounds TFPI, TFPI2, F2 GPR3 4881/4885KCNH2 1185/4885ACHE 1989/4885
US-20030162959-A1 Method for the preparation of 6alpha-fluoro corticosteroids HSD3B1, CYP2F1, HSD3B2 GPR3 628/4885KCNH2 2142/4885ACHE 1241/4885
US-12559514-B2 Synthesis of fluorinated nucleotides NUDT1, NSUN2, PNP GPR3 1241/4885KCNH2 383/4885ACHE 1747/4885
US-20250066294-A1 METHOD FOR PREPARING IONIC COMPOUNDS TST, MRPS23, SRMS GPR3 2247/4885KCNH2 201/4885ACHE 4044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.