Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 7/20 | 0.37 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619944 | 0.97 | LMNA (0.60) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL8379830 | 0.96 | LMNA (0.53) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL8378015 | 0.96 | LMNA (0.56) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL1557465 | 0.96 | LMNA (0.59) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL15489155 | 0.93 | LMNA (0.51) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL8373468 | 0.93 | LMNA (0.51) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL9189596 | 0.93 | LMNA (0.56) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL9237406 | 0.92 | LMNA (0.55) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL8905699 | 0.92 | LMNA (0.55) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL8905505 | 0.92 | SMN1; SMN2 (0.57) | LMNACYP2C19HIF1ASMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658239-B2 | Coating method for a folded balloon | B. BRAUN MELSUNGEN AG (DE) | 2014-02-25 | — | — | US | disclosed |
| US-20130066268-A1 | Coating Method for a Folded Balloon | B. BRAUN MELSUNGEN AG (DE) | 2013-03-14 | — | — | US | disclosed |