Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 7/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619944 | 0.95 | LMNA (0.60) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL1557465 | 0.93 | LMNA (0.59) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL14769256 | 0.92 | LMNA (0.56) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL9189596 | 0.91 | LMNA (0.56) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL8378015 | 0.91 | LMNA (0.56) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL8905505 | 0.90 | SMN1; SMN2 (0.57) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL8905699 | 0.90 | LMNA (0.55) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL9581262 | 0.88 | LMNA (0.57) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| Hydrochloric Acid SCHEMBL10429710 | 0.88 | SMN1; SMN2 (0.56) | LMNACYP2C19HIF1ASMN1; SMN2EGFR | |
| SCHEMBL10429709 | 0.88 | LMNA (0.54) | LMNACYP2C19HIF1ASMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530343-B1 | WATER SOLUBLE, NON-IONIC X-RAY CONTRASTING AGENTS AND PROCESS FOR PRODUCING THE SAME | KOEHLER CHEMIE DR FRANZ (DE) | 1995-09-20 | — | — | EP | disclosed |
| EP-0530343-A1 | WATER SOLUBLE, NON-IONIC X-RAY CONTRASTING AGENTS AND PROCESS FOR PRODUCING THE SAME. | KOEHLER CHEMIE DR FRANZ (DE) | 1993-03-10 | — | — | EP | disclosed |
| WO-1992016498-A1 | WATER SOLUBLE, NON-IONIC X-RAY CONTRASTING AGENTS AND PROCESS FOR PRODUCING THE SAME | Dr. Franz Köhler Chemie GmbH (DE) | 1992-10-01 | — | — | WO | disclosed |