SCHEMBL1476947

SCHEMBL1476947

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nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.47
ALDH1A1 P00352 3/20 0.46
MAPT P10636 1/20 0.46
FAAH O00519 3/20 0.44
MME P08473 2/20 0.44
ACE P12821 1/20 0.44
CPA1 P15085 1/20 0.44
ACE2 Q9BYF1 1/20 0.44
KDM4E B2RXH2 2/20 0.43
TSHR P16473 1/20 0.42
SLC6A5 Q9Y345 1/20 0.42
LTA4H P09960 2/20 0.40
RAB9A P51151 1/20 0.39
HSD17B10 Q99714 1/20 0.39
LDHA P00338 1/20 0.38
SRR Q9GZT4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1476944 1.00 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1MAPTFAAHMME
SCHEMBL2554949 0.83 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1MAPTFAAHMME
SCHEMBL13043948 0.83 LDHA (0.36) SMN1; SMN2ALDH1A1MAPTFAAHMME
SCHEMBL28571485 0.83 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1MAPTFAAHMME
SCHEMBL4572566 0.81 ALDH1A1 (0.51) SMN1; SMN2ALDH1A1MAPTFAAHMME
SCHEMBL2805775 0.81 ALDH1A1 (0.51) SMN1; SMN2ALDH1A1MAPTFAAHMME
SCHEMBL4811341 0.80 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1MAPTFAAHMME
SCHEMBL964581 0.80 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1MAPTFAAHMME
SCHEMBL4189346 0.80 ALDH1A1 (0.50) SMN1; SMN2ALDH1A1MAPTFAAHMME
SCHEMBL10076082 0.80 ALDH1A1 (0.50) SMN1; SMN2ALDH1A1MAPTFAAHMME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240350649-A1 TREATMENT AND DIAGNOSIS OF IMMUNE DISORDERS RELATING TO ABERRANT IMMUNE CELLS OCTAGON THERAPEUTICS, INC. 2024-10-24 US claimed
CN-119800361-A Application method of TFT metal film etching solution 昆山欣谷微电子材料有限公司 2025-04-11 CN disclosed
US-20240350649-A1 TREATMENT AND DIAGNOSIS OF IMMUNE DISORDERS RELATING TO ABERRANT IMMUNE CELLS OCTAGON THERAPEUTICS, INC. 2024-10-24 US disclosed
US-20130303466-A1 Chemosensory Receptor Ligand-Based Therapies ELCELYX THERAPEUTICS, INC. (US) 2013-11-14 US disclosed
US-20130303466-A1 Chemosensory Receptor Ligand-Based Therapies ELCELYX THERAPEUTICS, INC. (US) 2013-11-14 US disclosed
WO-2012054527-A2 CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES ELCELYX THERAPEUTICS, INC. (US) 2012-04-26 WO disclosed
US-20110171267-A1 ANTI-FUNGAL COMPOSITION Immunitor USA, Inc. 2011-07-14 US disclosed
US-7914799-B2 Vaccine; heat deactivated antigen; induce immunology response Immunitor USA, Inc. (US) 2011-03-29 US disclosed
WO-2003018051-A1 ANTI-FUNGAL COMPOSITION JIRA VIC (US) 2003-03-06 WO disclosed
US-20030039667-A1 Anti-fungal composition IMMUNITOR USA INC. 2003-02-27 US disclosed
US-6191168-B1 BACTERICIDES Rubenstein, Edward 2001-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130303466-A1 Chemosensory Receptor Ligand-Based Therapies GPR119, TAS1R2, TAS2R1 SMN1; SMN2 2361/4885ALDH1A1 796/4885MAPT 4181/4885
US-20240350649-A1 TREATMENT AND DIAGNOSIS OF IMMUNE DISORDERS RELATING TO ABERRANT IMMUNE CELLS CD74, SERPINA6, CD2BP2 SMN1; SMN2 3376/4885ALDH1A1 2933/4885MAPT 4500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.