Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | PTPRF | P10586 | 5/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10041340 | 0.97 | KDM4E (0.38) | KDM4ENPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL14770636 | 0.95 | CASP3 (0.36) | KDM4ENPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL15294180 | 0.94 | CHEK2 (0.35) | KDM4ENPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL14770629 | 0.94 | KDM4E (0.38) | KDM4ENPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL14867943 | 0.91 | KMT2A (0.38) | KDM4EMAPTALDH1A1MEN1HPGD | |
| SCHEMBL14770574 | 0.91 | KDM4E (0.43) | KDM4EMEN1RAB9AKMT2ACHEK2 | |
| SCHEMBL14770575 | 0.91 | ALOX5 (0.41) | NPC1MAPTCHEK2ATMPTPRF | |
| SCHEMBL14867964 | 0.91 | CHEK2 (0.34) | KDM4ENPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL14770637 | 0.90 | PTPRF (0.34) | KDM4ECHEK2CASP3SENP7SENP6 | |
| SCHEMBL14770645 | 0.90 | KMT2A (0.37) | KDM4ENPC1MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | TDO2, AHR, NOC2L | KDM4E 1763/4885NPC1 3134/4885MAPT 2242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.