Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PTPRF | P10586 | 9/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 9/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.36 |
| ▸ | PRKDC | P78527 | 5/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15294178 | 0.92 | ALOX5 (0.40) | ALOX5PTPRFPTPN2PTPN1PRKDC | |
| SCHEMBL14770569 | 0.91 | KDM4E (0.38) | PTPRFPTPN2PTPN1CHEK2HSP90AA1 | |
| SCHEMBL10041340 | 0.89 | KDM4E (0.38) | PTPRFPTPN2PTPN1CHEK2ATM | |
| SCHEMBL22107631 | 0.88 | ALOX5 (0.53) | ALOX5PRKDCPIK3CDPIK3CBCHEK2 | |
| SCHEMBL21946606 | 0.88 | ALOX5 (0.53) | ALOX5PRKDCPIK3CDPIK3CBCHEK2 | |
| SCHEMBL14770594 | 0.88 | ALOX5 (0.51) | ALOX5PTPRFPTPN2PTPN1PRKDC | |
| SCHEMBL14770636 | 0.87 | CASP3 (0.36) | PTPRFPTPN2PTPN1PRKDCCHEK2 | |
| SCHEMBL17253862 | 0.87 | ALOX5 (0.39) | ALOX5PTPRFPTPN2PTPN1PRKDC | |
| SCHEMBL15294180 | 0.86 | CHEK2 (0.35) | PTPRFPTPN2PTPN1CHEK2HSP90AA1 | |
| SCHEMBL20715118 | 0.85 | ALOX5 (0.51) | ALOX5PRKDCPIK3CDPIK3CBCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | TDO2, AHR, NOC2L | ALOX5 1836/4885PTPRF 4476/4885PTPN2 2467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.