SCHEMBL14770901

SCHEMBL14770901

COc1ccccc1-c1cc(-c2ccccc2)c(C=O)[nH]1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPO P05164 1/20 0.49
KDM4E B2RXH2 4/20 0.49
KMT2A Q03164 3/20 0.49
ALDH1A1 P00352 3/20 0.49
MEN1 O00255 2/20 0.49
RAB9A P51151 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MAPT P10636 1/20 0.49
HPGD P15428 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
NPC1 O15118 1/20 0.47
ATM Q13315 1/20 0.47
ERN1 O75460 1/20 0.45
CCNB2 O95067 1/20 0.45
CDK1 P06493 1/20 0.45
CCNB1 P14635 1/20 0.45
GSK3A P49840 1/20 0.45
GSK3B P49841 1/20 0.45
CDK5 Q00535 1/20 0.45
CDK5R1 Q15078 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL185969 0.80 NPC1 (0.53) KDM4EALDH1A1RAB9ASMN1; SMN2MAPT
SCHEMBL14770899 0.75 CCNB2 (0.41) MPOKDM4EKMT2AALDH1A1MEN1
SCHEMBL31078212 0.74 MPO (0.62) MPOKDM4EKMT2AALDH1A1MEN1
SCHEMBL30136447 0.72 ALDH1A1 (0.58) KDM4EALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL294721 0.72 ALDH1A1 (0.58) KDM4EALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL28442582 0.72 ALDH1A1 (0.45) KDM4EKMT2AALDH1A1MEN1RAB9A
SCHEMBL6937695 0.71 MAPK14 (0.49) MPOKDM4EKMT2AALDH1A1MEN1
SCHEMBL9754385 0.70 ERN1 (0.45) KDM4EKMT2AALDH1A1MEN1RAB9A
Biphenyl SCHEMBL9989359 0.70 ALDH1A1 (0.56) KDM4EALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL30017788 0.70 ALDH1A1 (0.56) KDM4EALDH1A1RAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013035303-A1 ORGANIC THIN FILM SOLAR CELL MATERIAL 出光興産株式会社 (JP) 2013-03-14 WO disclosed