SCHEMBL1477096

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1477845	0.90	MAPKAPK5 (0.59)	MAPKAPK5BTKAURKAAURKBPTK6
	SCHEMBL12443314	0.89	MAPKAPK5 (0.57)	MAPKAPK5AURKAAURKBPTK6BRD4
	SCHEMBL1478109	0.86	MAPKAPK5 (0.78)	MAPKAPK5AURKAAURKBPTK6ACVR1
	SCHEMBL2217998	0.86	MAPKAPK5 (0.74)	MAPKAPK5BTKAURKAAURKBPTK6
	SCHEMBL2217134	0.85	MAPKAPK5 (0.82)	MAPKAPK5BTKABL1AURKAAURKB
	SCHEMBL1475901	0.85	MAPKAPK5 (1.00)	MAPKAPK5AURKAAURKBPTK6ACVR1
	SCHEMBL2219234	0.84	MAPKAPK5 (0.83)	MAPKAPK5AURKAAURKBPTK6ACVR1
	SCHEMBL2218746	0.83	MAPKAPK5 (0.78)	MAPKAPK5AURKAAURKBPTK6ACVR1
	SCHEMBL2217920	0.83	MAPKAPK5 (0.78)	MAPKAPK5AURKAAURKBPTK6ACVR1
	SCHEMBL14369552	0.82	MAPKAPK5 (0.51)	MAPKAPK5BTKABL1BCRACVR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.