Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 6/20 | 0.34 |
| ▸ | PPARD | Q03181 | 6/20 | 0.34 |
| ▸ | PPARA | Q07869 | 6/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14772124 | 0.92 | BBOX1 (0.58) | BBOX1LMNASLC22A6APEX1TSHR | |
| SCHEMBL16075145 | 0.81 | PTGS1 (0.41) | BBOX1LMNAPDE4A | |
| SCHEMBL15559792 | 0.79 | BBOX1 (0.58) | BBOX1LMNASLC22A6MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8110106 | 0.77 | BBOX1 (0.73) | BBOX1LMNASLC22A6TSHRNFKB1 | |
| SCHEMBL18088312 | 0.77 | BBOX1 (0.40) | BBOX1LMNAMEN1KMT2A | |
| SCHEMBL14608930 | 0.77 | ACHE (0.52) | BBOX1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL918271 | 0.77 | BBOX1 (0.46) | BBOX1LMNAPDE4A | |
| SCHEMBL1109583 | 0.75 | BBOX1 (0.67) | BBOX1SLC22A6TSHRAKR1B1PPARG | |
| SCHEMBL6238274 | 0.74 | HTT (0.60) | LMNAKMT2A | |
| SCHEMBL6236738 | 0.74 | HTT (0.60) | LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487480-B2 | Zwitterionic reagents | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2016-11-08 | — | — | US | disclosed |
| US-20160274094-A1 | ZWITTERIONIC REAGENTS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2016-09-22 | — | — | US | disclosed |
| US-20160274094-A1 | ZWITTERIONIC REAGENTS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2016-09-22 | — | — | US | disclosed |
| US-9353056-B2 | — | — | 2016-05-31 | — | — | US | disclosed |
| US-20130065325-A1 | ZWITTERIONIC REAGENTS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065325-A1 | ZWITTERIONIC REAGENTS | BTD, HLCS, WIZ | BBOX1 361/4885LMNA 699/4885SLC22A6 2739/4885 |
| US-20160274094-A1 | ZWITTERIONIC REAGENTS | BTD, HLCS, WIZ | BBOX1 361/4885LMNA 699/4885SLC22A6 2739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.