SCHEMBL14775387

SCHEMBL14775387

Nc1c(S(=O)(=O)O)ccc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNG2 P59768 5/20 0.41
GNB1 P62873 5/20 0.41
HSD17B10 Q99714 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C9 P11712 2/20 0.41
ALOX15 P16050 2/20 0.41
DAPK1 P53355 1/20 0.37
SUMO2 P61956 1/20 0.37
SUMO1 P63165 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP2 Q9HC62 1/20 0.37
SENP1 Q9P0U3 1/20 0.37
ALDH1A1 P00352 4/20 0.36
MAPT P10636 3/20 0.36
RECQL P46063 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
KDM4E B2RXH2 1/20 0.36
NSD2 O96028 1/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL14471802 0.97 GNG2 (0.40) GNG2GNB1HSD17B10CYP1A2CYP2C9
SCHEMBL28349046 0.86 MAPT (0.41) GNG2GNB1HSD17B10CYP1A2CYP2C9
SCHEMBL28147663 0.84 TSHR (0.40) GNG2GNB1HSD17B10CYP1A2CYP2C9
SCHEMBL2521856 0.82 TSHR (0.39) GNG2GNB1HSD17B10CYP1A2CYP2C9
SCHEMBL27534240 0.80 ALDH1A1 (0.43) HSD17B10CYP2C9ALOX15ALDH1A1MAPT
SCHEMBL28166154 0.79 TSHR (0.36) GNG2GNB1HSD17B10CYP1A2CYP2C9
SCHEMBL1143477 0.79 TTR (0.46) GNG2GNB1HSD17B10CYP1A2CYP2C9
SCHEMBL8165203 0.78 MAPT (0.38) GNG2GNB1HSD17B10CYP1A2CYP2C9
SCHEMBL8933866 0.77 CHAT (0.38) HSD17B10CYP2C9MAPTTSHRSMN1; SMN2
SCHEMBL15771318 0.77 PTGS2 (0.42) DAPK1SUMO2SUMO1SENP7SENP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3288107-B1 LEAD STORAGE BATTERY HITACHI CHEMICAL CO LTD (JP) 2019-02-20 EP disclosed
EP-3288107-A1 LEAD STORAGE BATTERY Hitachi Chemical Company, Ltd. (JP) 2018-02-28 EP disclosed
EP-2571091-B1 LEAD STORAGE BATTERY HITACHI CHEMICAL CO LTD (JP) 2017-11-29 EP disclosed
US-20130099749-A1 LEAD-ACID BATTERY SHIN-KOBE ELECTRIC MACHINERY CO., LTD. (JP) 2013-04-25 US disclosed
EP-2571091-A1 LEAD STORAGE BATTERY Shin-Kobe Electric Machinery Co., Ltd. (JP) 2013-03-20 EP disclosed