Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28147663 | 0.85 | TSHR (0.40) | CHATSNCATSHRSMN1; SMN2HDAC4 | |
| SCHEMBL8909039 | 0.81 | HNF4A (0.43) | CHATSNCATSHRSMN1; SMN2HDAC4 | |
| SCHEMBL2521856 | 0.80 | TSHR (0.39) | CHATSNCATSHRSMN1; SMN2HDAC4 | |
| SCHEMBL13726094 | 0.78 | TSHR (0.47) | TSHRSMN1; SMN2CA1CA2MMP2 | |
| SCHEMBL2521857 | 0.78 | PTGS2 (0.44) | CHATSNCATSHRSMN1; SMN2HDAC4 | |
| SCHEMBL28019701 | 0.78 | PGAM1 (0.49) | CHATSNCATSHRSMN1; SMN2HDAC4 | |
| SCHEMBL14775387 | 0.77 | GNG2 (0.41) | SNCATSHRSMN1; SMN2HDAC4HDAC2 | |
| SCHEMBL28166154 | 0.77 | TSHR (0.36) | CHATSNCATSHRSMN1; SMN2HDAC4 | |
| SCHEMBL28898442 | 0.77 | USP7 (0.42) | TSHRSMN1; SMN2MMP2MAPTHTT | |
| SCHEMBL232659 | 0.77 | CASP1 (0.47) | CHATSNCATSHRSMN1; SMN2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026177-A1 | PROCESS FOR PREPARING ARYLACETIC ACID AND ARYLPROPIONIC ACID DERIVATIVES | HOECHST CELANESE CORPORATION (US) | 1996-08-29 | — | — | WO | claimed |
| US-5536874-A | Process for preparing arylacetic acid and arylpropionic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1996-07-16 | — | — | US | claimed |
| WO-1996026177-A1 | PROCESS FOR PREPARING ARYLACETIC ACID AND ARYLPROPIONIC ACID DERIVATIVES | HOECHST CELANESE CORPORATION (US) | 1996-08-29 | — | — | WO | disclosed |
| US-5536874-A | Process for preparing arylacetic acid and arylpropionic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |