Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.51 |
| ▸ | KDM4A | O75164 | 2/20 | 0.51 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.51 |
| ▸ | KDM6B | O15054 | 1/20 | 0.51 |
| ▸ | KDM6A | O15550 | 1/20 | 0.51 |
| ▸ | TET3 | O43151 | 1/20 | 0.51 |
| ▸ | KDM4B | O94953 | 1/20 | 0.51 |
| ▸ | KDM5C | P41229 | 1/20 | 0.51 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.51 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.51 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.51 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.51 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.51 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342871 | 0.86 | TP53 (0.61) | L3MBTL1TP53ALOX15ATMMEN1 | |
| SCHEMBL14775787 | 0.83 | TP53 (0.53) | L3MBTL1TP53ALOX15ATMMEN1 | |
| SCHEMBL14775769 | 0.81 | ATM (0.56) | L3MBTL1TP53ALOX15ATMMEN1 | |
| SCHEMBL28463407 | 0.79 | KDM4E (0.74) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL15703122 | 0.79 | KDM4E (0.68) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL7772896 | 0.76 | KDM4E (0.68) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL7032474 | 0.73 | IDO1 (0.61) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL8342736 | 0.73 | MMP2 (0.55) | KDM4EL3MBTL1EGLN1TP53TOP2A | |
| SCHEMBL28781361 | 0.72 | L3MBTL1 (0.57) | KDM4EL3MBTL1TP53ALOX15MEN1 | |
| SCHEMBL13286792 | 0.71 | ATM (0.54) | KDM4EL3MBTL1TP53ALOX15ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963272-B1 | HYDROXYQUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2013-03-20 | — | — | EP | claimed |
| EP-1963272-B1 | HYDROXYQUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2013-03-20 | — | — | EP | disclosed |